Results 321 to 330 of about 451,143 (385)

Forces involved in the Conformational Stability of Nucleic Acids

Nature, 1969
ONE of the most important problems in research on nucleic acid is the understanding of the forces which maintain the helical structure. After the elucidation of the double helix by Watson and Crick1, the helical secondary structure of DNA was thought to derive its stability from hydrogen bonding between the base pair. The discovery that polynucleotides
J C, Maurizot, J, Brahms, F, Eckstein
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Conformational properties of nucleic acids in solution

International Journal of Quantum Chemistry, 2009
Principles which govern the conformational properties of nucleic acid structures in aqueous solution are derived from extensive nuclear magnetic resonance studies of nucleic acid components. These principles are then utilized to project the solution conformation of tRNA.
Ramaswamy H. Sarma, Steven S. Danyluk
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Conformation of Viral Nucleic Acids in Situ

1969
Publisher Summary The problems that are discussed in this chapter are confined to viruses, and to be more exact, to the question of similarities and differences between the structure and properties of usual forms of nucleic acids in solution and that of nucleic acids inside viral particles.
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Single molecule approaches of nucleic acids conformational changes

Methods, 2019
Single molecule approaches of nucleic acids conformational changes One of the primordial questions today in biology is: how does DNA regulate its own metabolism? In other words, what are the mechanisms that enables specific genes to be transcribed while others are silenced?
Lavelle, Christophe, Tardin, Catherine
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Conformational geometry and vibrational frequencies of nucleic acid chains

Biopolymers, 1975
AbstractNormal coordinate analysis of diethyl phosphate has been made, which predicts all observed Raman frequencies in the range 170–1300 cm−1. The force constants from this calculation have been transferred to a vibrational calculation for a simplified model of the backbone of nucleic acids, which also involves the OPO2−O phosphate group and the ...
E B, Brown, W L, Peticolas
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Alternative conformations of a nucleic acid four-way junction

Journal of Molecular Biology, 2000
A crystal structure of a 108 nucleotide RNA-DNA complex containing a four-way junction was solved at 3.1 A resolution. The structure of the junction differs substantially from the "stacked-X" conformation observed previously, due to a 135 degrees rotation of the branches.
J, Nowakowski, P J, Shim, C D, Stout, G F, Joyce   +3 more
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Recent Advances in Chain Conformation and Bioactivities of Triple-helix Polysaccharides.

Biomacromolecules, 2020
Natural polysaccharides derive from renewable biomass sources, and are regarded as environmentally friendly and sustainable polymers. As the third abundant biomacromolecule after protein and nucleic acid in nature, polysaccharides are also closely ...
Y. Meng, Fengzhi Lyu, Xiaojuan Xu, Lina Zhang   +3 more
semanticscholar   +1 more source

Copper(II)-Nucleic acid interactions—A conformational study

Journal of Theoretical Biology, 1979
Abstract The effect of copper complexation upon the conformational angles in mononucleotides and dinucleotides was studied using classical potential energy expressions. The geometrical parameters were taken from crystallographic reports on the base-metal complexes.
J, Bandekar, B K, Sathyanarayana
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Evolution of conformational principles in nucleic acids

International Journal of Quantum Chemistry, 2009
The analysis of conformations of nucleic acids and polynucleotides have been greatly simplified by the important observations that the nucleotide building blocks exhibit two classes of preferred conformations and that the flexibility in the polynucleotide chain resides mainly in the internucleotide PO linkages.
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Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute

Nature, 2023
Xiaopan Gao, Kun Shang, Kaixiang Zhu, Linyue Wang, Z. Mu, Xingke Fu, Xia Yu, B. Qin, Hongtao Zhu, Wei Ding, Sheng Cui   +10 more
semanticscholar   +1 more source