Results 331 to 340 of about 451,143 (385)

Conformational principles of nucleic acids

1981
From a conformational standpoint, nucleic acids are enormously complex. In order to rigorously describe, for example, the secondary structure of a repeating polynucleotide such as fibrous poly dA·dT, the values of twelve torsion angles must be ascertained (Figure 1.1); contrast this with a repeating polypeptide where only two conformation angles need ...
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Quantum-Mechanical Studies on the Conformation of Nucleic Acids and Their Constituents

1976
Publisher Summary This chapter discusses the results of the quantum-mechanical computations of the conformational properties of nucleic acids and their constituents, comparing the results obtained by different methods among themselves with the results of the empirical computations, and with the available experimental data as obtained by different ...
B, Pullman, A, Saran
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Influence of Lipid Membranes on the Conformational Transitions of Nucleic Acids

Journal of Biomolecular Structure and Dynamics, 1986
The conformational transitions of nucleic acids which were enclosed in reverse phase evaporation vesicles (REV) were studied by thermal denaturation with optical recording. Cloned fragments of double-stranded DNA containing 179 base pairs and 187 base pairs, respectively, and polyA.polyU were enclosed in REV with a yield up to every vesicle containing ...
B, Brosius, D, Riesner
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Conformational penalties: New insights into nucleic acid recognition

Current Opinion in Structural Biology
The energy cost accompanying changes in the structures of nucleic acids when they bind partner molecules is a significant but underappreciated thermodynamic contribution to binding affinity and specificity. This review highlights recent advances in measuring conformational penalties and determining their contribution to the recognition, folding, and ...
Ainan, Geng, Rohit, Roy, Hashim M, Al-Hashimi   +2 more
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Nucleic acid reactivity and conformation I. Deamination of cytosine by nitrous acid

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
Abstract The rate of deamination of cytosine to uracil by nitrous acid was measured under several sets of conditions for the following compounds: cytidine, cytidine 5′-phosphate, poly(cytidylic acid) (in both single-stranded and half-protonated double helix forms), and the poly(I) · poly(C) complex. The relative reactivity of nucleoside : nucleotide :
R, Shapiro, H, Yamaguchi
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Infrared Studies on the Backbone Conformation of Nucleic Acids

Israel Journal of Chemistry, 1974
AbstractThe presence and assignment of low frequency infrared bands characteristic of the A, B and C forms of DNA (Salmon Sperm and Micrococcus Lysodeikticus) and of synthetic poly (dA‐T): (dA‐T) and of polyribonucleotides‐A form are considered. The vibrational modes that may arise from the phosphate diester stretch of DNA backbone are investigated in ...
S. Brahms, J. Brahms, J. Pilet
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Optical activity and the conformation of polynucleotide models of nucleic acids

Journal of Molecular Biology, 1965
The interaction between polymers of adenylic and uridylic acids has been investigated using homopolyadenylate and homopolyuridylate, and copolymers containing various ratios of AMP and UMP randomly distributed. The measurements of circular dichroism in the region of 230 to 320 m μ indicate that the formation of the two-stranded poly (A + U)† helical ...
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Nucleic acid conformation: crystal structure of a naturally occurring dinucleoside phosphate (UpA).

Nature: New biology, 1971
N. Seeman, J. Sussman, H. Berman, Sung-Hou Kim   +3 more
semanticscholar   +1 more source

Dependence of purine 8C‐H exchange on nucleic acid conformation and base‐pairing geometry: A dynamic probe of DNA and RNA secondary structures

Biopolymers, 1985
J. Benevides, G. Thomas
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PARTITION STUDIES ON NUCLEIC ACIDS. I. INFLUENCE OF ELECTROLYTES, POLYMER CONCENTRATION AND NUCLEIC ACID CONFORMATION OF THE PARTITION IN THE DEXTRAN-POLYETHYLENE GLYCOL SYSTEM.

Biochimica et Biophysica Acta, 1965
P. Albertsson
semanticscholar   +1 more source