Results 101 to 110 of about 364,067 (350)

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Detection of Common Bacterial Causes of STIs among STD Clinic Attendees by Gram Stain and Culture versus the Microarray Nucleic Acid Hybridization Method

Central Asian Journal of Medical Sciences, 2017
Objectives: The purpose of the study was to determine the prevalence and etiology of predominant sexually transmitted infections (STIs) occurring among the STD and Gynecology Clinic attendees and to compare sensitivity and specificity of conventional ...
Jugderjav Badrakh, Bulbul Aumakhan, Baatarkhuu Oidov, Unursaikhan Ganbat, Erdenechimeg Choijiljav, Naranbat Nymadawa, Nymadawa Pagvajav   +6 more
doaj   +1 more source

ClampFISH detects individual nucleic-acid molecules using click chemistry based amplification

Nature Biotechnology, 2018
Methods for detecting single nucleic acids in cell and tissues, such as fluorescence in situ hybridization (FISH), are limited by relatively low signal intensity and nonspecific probe binding.
S. Rouhanifard, Ian A. Mellis, Margaret C. Dunagin, Sareh Bayatpour, Connie L. Jiang, Ian P. Dardani, Orsolya Symmons, Benjamin L. Emert, E. Torre, Allison Coté, Alessandra M. Sullivan, J. Stamatoyannopoulos, A. Raj   +12 more
semanticscholar   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

FastTag™ Nucleic Acid Labeling System: A Versatile Method for Incorporating Haptens, Fluorochromes and Affinity Ligands into DNA, RNA and Oligonucleotides

BioTechniques, 1998
The FastTag™ Nucleic Acid Labeling System couples haptens, fluorochromes or affinity ligands to any nucleic acid by attaching a universal, photo- or heat-activatable moiety to which any sulfhydryl-reactive compound can be linked.
Steven G. Daniel, Mark E. Westling, Michele S. Moss, Brian D. Kanagy   +3 more
doaj   +1 more source

A Bio‐Inspired Perspective on Materials Sustainability

Advanced Materials, EarlyView.
This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier, Khashayar Razghandi, Peter Fratzl   +2 more
wiley   +1 more source

Nucleic Acid Sandwich Hybridization Assay with Quantum Dot-Induced Fluorescence Resonance Energy Transfer for Pathogen Detection

Sensors, 2012
This paper reports a nucleic acid sandwich hybridization assay with a quantum dot (QD)-induced fluorescence resonance energy transfer (FRET) reporter system.
Cheng-Chung Chou, Yi-Han Huang
doaj   +1 more source

Sustainable Smart Packaging from Protein Nanofibrils

Advanced Materials, EarlyView.
Smart packaging can extend shelf life and improve food quality monitoring. This study introduces a novel smart packaging solution using amyloid fibrils and red radish anthocyanins to monitor seafood spoilage. These findings show that these films effectively indicate shrimp freshness and possess high antibacterial and antioxidant properties, offering a ...
Mohammad Peydayesh, Alan Kovacevic, Leah Hoffmann, Felix Donat, Ciatta Wobill, Laura Baraldi, Jiangtao Zhou, Christoph R. Müller, Raffaele Mezzenga   +8 more
wiley   +1 more source

Stacking correlation length in single-stranded DNA [PDF]

Nucleic Acids Research, 2024
Base stacking is crucial in nucleic acid stabilization, from DNA duplex hybridization to single-stranded DNA (ssDNA) protein binding. While stacking energies are tiny in ssDNA, they are inextricably mixed with hydrogen bonding in DNA base pairing, making their measurement challenging. We conduct unzipping experiments with optical tweezers of short poly-
arxiv   +1 more source

Nucleic acid hybridization studies on Microbacterium, Curtobacterium, Agromyces and related taxa.

Journal of General Microbiology, 1982
Thirty strains of Agromyces, Arthrobacter, Curtobacterium, Brevibacterium, Corynebacterium and Microbacterium, exhibiting the rare peptidoglycan of group B, were subjected to extensive nucleic acid hybridization studies.
H. Döpfer, E. Stackebrandt, F. Fiedler
semanticscholar   +1 more source