DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
Advanced Materials, EarlyView.DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
Using Peptide Nucleic Acid Hybridization Probes for Qualitative and Quantitative Analysis of Nucleic Acid Therapeutics by Capillary Electrophoresis. [PDF]
Anal Chem, 2023 Hutanu A +5 more
europepmc +1 more source
Flexibility of nucleic acids: from DNA to RNA [PDF]
arXiv, 2015 The structural flexibility of nucleic acids plays a key role in many fundamental life processes, such as gene replication and expression, DNA-protein recognition, and gene regulation. To obtain a thorough understanding of nucleic acid flexibility, extensive studies have been performed using various experimental methods and theoretical models.
arxiv
Analytical Chemistry, 2010 A ternary surface monolayer, consisting of coassembled thiolated capture probe, mercaptohexanol and dithiothreitol, is shown to offer dramatic improvements in the signal-to-noise characteristics of electrochemical DNA hybridization biosensors based on ...
Jie Wu +4 more
semanticscholar +1 more source
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Recent developments in the characterization of nucleic acid hybridization kinetics. [PDF]
Curr Opin Biomed Eng, 2021 Chen YI +6 more
europepmc +1 more source
Scanning single-molecule counting system for Eprobe with highly simple and effective approach.
PLoS ONE, 2020 Here, we report a rapid and ultra-sensitive detection technique for fluorescent molecules called scanning single molecular counting (SSMC). The method uses a fluorescence-based digital measurement system to count single molecules in a solution.
Takeshi Hanami +13 more
doaj +1 more source
Flexibility-Rigidity Index for Protein-Nucleic Acid Flexibility and Fluctuation Analysis [PDF]
arXiv, 2015 Protein-nucleic acid complexes are important for many cellular processes including the most essential function such as transcription and translation. For many protein-nucleic acid complexes, flexibility of both macromolecules has been shown to be critical for specificity and/or function. Flexibility-rigidity index (FRI) has been proposed as an accurate
arxiv
Multiplexed Bio‐detection on an Interferometric Optical Waveguide Assembly
Advanced Materials Interfaces, EarlyView.Multiplexed remote bio‐detection is demonstrated through an image conduit composed of 3012 individual cores and coated with interferometric layers. The proof of concept of biodetection is performed through the kinetic monitoring of two complementary DNA strands hybridization paving the way for applications in multiplex in situ biosensing, and ...
Oleksii Bratash +6 more
wiley +1 more source
A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions. [PDF]
Nat Commun, 2021 Liu B +8 more
europepmc +1 more source