Results 141 to 150 of about 114,253 (306)

A quantitative model predicts how m ⁶ A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions [PDF]

, 2020
Bei Liu, Honglue Shi, Atul Rangadurai, Felix Nußbaumer, Chia-Chieh Chu, Kevin Erharter, David A. Case, Christoph Kreutz, Hashim M. Al‐Hashimi   +8 more
openalex   +1 more source

A Closed‐Loop‐Capable Neural Interface Platform for Deep Brain Modulation via Integrated Non‐Viral Gene Delivery, NIR Optogenetics, and Electrophysiological Recording

Advanced Science, EarlyView.
A multifunctional, 3D porous neural interface combines non‐viral gene delivery and NIR optogenetics to enable minimally invasive, closed‐loop modulation of deep‐brain circuits. Abstract Closed‐loop neuromodulation requires precise, stable, and cell‐specific control of neural circuits with minimal invasiveness.
Chao‐Yi Chu, Zih‐Huei Chen, Chun‐Wei Liang, Pu‐Wei Wu, Wei‐Qing Guo, Bo‐Wei Chen, Chih‐Chia Huang, Ssu‐Ju Li, Ching‐Wen Chang, Yao‐Wen Liang, Shun‐An Kan, Yu‐Chun Lo, Wei‐Chen Huang, You‐Yin Chen, San‐Yuan Chen   +14 more
wiley   +1 more source

Versatile recombinase polymerase amplification via proximity hybridization-triggered amplification conversion for detecting diverse nucleic acid targets

Lutan Zhang, Yuxiao Ma, Wenbo Wang, Jian Zhang, Yixi Zhou, Yanru Huang, Xingmei Yao, Jieqiong Xie, Lulu Xu, Yunsheng Ge   +9 more
openalex   +1 more source

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source

The Use of Atomic Force Microscopy for 3D Analysis of Nucleic Acid Hybridization on Microarrays. [PDF]

Acta Naturae, 2015
Dubrovin EV, Presnova GV, Rubtsova MY, Egorov AM, Grigorenko VG, Yaminsky IV.   +5 more
europepmc   +1 more source

Peptide Nucleic Acid Fluorescence In Situ Hybridization-Based Identification of Candida albicans and Its Impact on Mortality and Antifungal Therapy Costs

, 2006
Graeme N. Forrest, K. Mankes, Mary Ann Jabra‐Rizk, Elizabeth Weekes, J. Kristie Johnson, Durry P. Lincalis, Richard A. Venezia   +6 more
openalex   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Visualized Nucleic Acid Hybridization Lateral Flow Strip Integrating with Microneedle for the Point-of-Care Authentication of Ophiocordyceps sinensis. [PDF]

Int J Mol Sci
Liu H, Wang X, Tian H, Yuan Y, Wang J, Cheng Y, Sun L, Chen H, Song X.   +8 more
europepmc   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids?*

, 2020
Pratik S. Randeria, Matthew R. Jones, Kevin L. Kohlstedt, Resham J. Banga, Mónica Olvera de la Cruz, George C. Schatz, Chad A. Mirkin   +6 more
openalex   +4 more sources