Results 231 to 240 of about 316,767 (328)

N‐Amino Peptide–Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies

open access: yesAdvanced NanoBiomed Research, EarlyView.
A neuron‐targeting drug delivery system is developed by incorporating the tau‐specific N‐amino peptide, mxyl‐NAP2, with graphene quantum dots (GQDs) and encapsulating the complex into small extracellular vesicles functionalized with a neuron‐targeting ligand.
Runyao Zhu   +5 more
wiley   +1 more source

Complex Donuts: Small Variations in DNA Sequence Dictate Pathway Complexity in DNA Nanotoroids

open access: yesAngewandte Chemie, EarlyView.
Chemical information encoded in the sequence of DNA amphiphiles enables the selective formation of kinetically trapped DNA nanotoroids through a complex self‐assembly pathway. The toroids are formed as on‐pathway structures via a competitive mechanism only when a toroid‐selective DNA sequence is used.
Muhammad Ghufran Rafique   +9 more
wiley   +2 more sources

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

open access: yesAdvanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos   +2 more
wiley   +1 more source

Thermodynamics of Water Displacement from Binding Sites and its Contributions to Supramolecular and Biomolecular Affinity

open access: yesAngewandte Chemie, EarlyView.
The affinity between a guest and a macrocyclic host depends strongly on the water encapsulated inside the host cavity, with free‐energy variations on the order of 20 kcal mol−1 being possible even in the absence of direct host‐guest interactions. This conclusion–which contrasts alternative views–can be drawn from molecular dynamics simulations for the ...
Jeffry Setiadi   +3 more
wiley   +2 more sources

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai   +5 more
wiley   +1 more source

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