Results 291 to 300 of about 364,067 (350)
Some of the next articles are maybe not open access.

Labelling nucleic acids for hybridization

Nature, 1987
The enormous utility of labelled nucleic acid probes has encouraged the development, over the past decade, of many efficient and reliable labelling methods.
C. R. Mundy, M. W. Cunningham
openaire   +3 more sources

Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Mediated Lateral Flow Nucleic Acid Assay.

ACS Nano, 2020
The lateral flow assay is one of the most convenient analytical techniques for analyzing the immune response, but its applicability to precise genetic analyses is limited by the false-positive signal and tedious and inefficient hybridization steps. Here,
Xusheng Wang   +8 more
semanticscholar   +1 more source

Identification of foodborne pathogens by nucleic acid hybridization [PDF]

open access: possibleInternational Journal of Food Microbiology, 1991
Nucleic acid hybridization methods have been developed and used to identify microorganisms in foods. Tests performed on mixed cultures save the time required to establish pure cultures. Enterotoxigenic or invasive strains of foodborne bacterial pathogens are detected with probes that identify genes responsible for virulence.
Walter E. Hill, Stacye P. Keasler
openaire   +2 more sources

Camera-based ratiometric fluorescence transduction of nucleic acid hybridization with reagentless signal amplification on a paper-based platform using immobilized quantum dots as donors.

Analytical Chemistry, 2014
Paper-based diagnostic assays are gaining increasing popularity for their potential application in resource-limited settings and for point-of-care screening.
M. O. Noor, U. Krull
semanticscholar   +1 more source

A DNA origami nanorobot controlled by nucleic acid hybridization.

Small, 2014
A prototype for a DNA origami nanorobot is designed, produced, and tested. The cylindrical nanorobot (diameter of 14 nm and length of 48 nm) with a switchable flap, is able to respond to an external stimulus and reacts by a physical switch from a ...
E. Torelli   +7 more
semanticscholar   +1 more source

Electrostatic nucleic acid nanoassembly enables hybridization chain reaction in living cells for ultrasensitive mRNA imaging.

Journal of the American Chemical Society, 2015
Efficient approaches for intracellular delivery of nucleic acid reagents to achieve sensitive detection and regulation of gene and protein expressions are essential for chemistry and biology.
Zhan Wu   +3 more
semanticscholar   +1 more source

Single nanoparticle ICP-MS DNA Assay based on Hybridization Chain Reaction Mediated Spherical Nucleic Acids Assembly.

Analytical Chemistry, 2020
The detection of nucleic acid is critical for clinic diagnostics. The single nanoparticle inductively coupled plasma mass spectrometry (SP-ICP-MS) has demonstrated unique advantages for nucleic acid detec-tion. Here we reported the development of a novel
Bang-Rui Li   +3 more
semanticscholar   +1 more source

Luminescence resonance energy transfer-based nucleic acid hybridization assay on cellulose paper with upconverting phosphor as donors.

Analytical Chemistry, 2014
A bioassay based on DNA hybridization on cellulose paper is a promising format for gene fragment detection that may be suited for in-field and rapid diagnostic applications.
Feng Zhou, M. O. Noor, U. Krull
semanticscholar   +1 more source

Hybridization of Nucleic Acids to Chromosomes

1972
Ever since the method of molecular hybridization of nucleic acids was conceived, a number of biologists have tried to hybridize labeled RNA or DNA to chromosomes for detection by autoradiography. The first report was by French and Kitzmiller (1967), who hybridized 3H-DNA from Drosophila melanogaster to the DNA of the salivary chromosomes of the same ...
Dale M. Steffensen, D. E. Wimber
openaire   +3 more sources

Paper-based solid-phase nucleic acid hybridization assay using immobilized quantum dots as donors in fluorescence resonance energy transfer.

Analytical Chemistry, 2013
A paper-based solid-phase assay is presented for transduction of nucleic acid hybridization using immobilized quantum dots (QDs) as donors in fluorescence resonance energy transfer (FRET).
M. O. Noor, Anna Shahmuradyan, U. Krull
semanticscholar   +1 more source

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