Results 271 to 280 of about 471,867 (378)

Breaking the stoichiometric limit of padlock probe ligation via catalytic hairpin assembly-and-cyclization. [PDF]

Nucleic Acids Res
Meng F, Ma Y, Sun M, Tian B, Zhou Z, Dong Z, Tian B.   +6 more
europepmc   +1 more source

Candida bracarensis Detected among Isolates of Candida glabrata by Peptide Nucleic Acid Fluorescence In Situ Hybridization: Susceptibility Data and Documentation of Presumed Infection

, 2007
Justin A. Bishop, Nancy Chase, Shelley S. Magill, Cletus P. Kurtzman, Mark J. Fiandaca, William G. Merz   +5 more
openalex   +2 more sources

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Extracellular vesicle-based delivery systems for nucleic acid therapeutics. [PDF]

Mol Ther Nucleic Acids
Zhang X, Liu X, Zhou Q, Yao K.
europepmc   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

Systematic performance evaluation and application validation of an end-to-end NGS workstation. [PDF]

Sci Rep
Xie W, Yang C, Ren S.
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

One-pot CRISPR-based point of care platform for rapid, specific and sensitive detection of HPV 16 without pre-amplification. [PDF]

Microsyst Nanoeng
Chen Y, Chen Y, Zhang C, Cai Y, Zeng Z, Reboud J, Cooper JM, Shan H, Wang Y, Xu G.   +9 more
europepmc   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Decoding nucleic acid contributions to phase separation and ordering in biomolecular condensates. [PDF]

Nucleic Acids Res
Asnicar D, Codispoti S, Morasso C, Ferrarini A, Zanchetta G.   +4 more
europepmc   +1 more source