Results 71 to 80 of about 363,968 (255)
Fluorecently labeled bionanotransporters of nucleic acid based on carbon nanotubes [PDF]
Ukrainian Journal of Physics, 2009, Vol. 54, no. 1-2, pp. 207-215, 2012 Here we propose the approach to design of the new type of hybrids of oligonucleotides with fluorescein-functionalized single-walled carbon nanotubes. The approach is based on stacking interactions of functionalized nanotubes with pyrene residues in conjugates of oligonucleotides.
arxiv
What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids?* [PDF]
Journal of the American Chemical Society, 2015 The hybridization of free oligonucleotides to densely packed, oriented arrays of DNA modifying the surfaces of spherical nucleic acid (SNA)-gold nanoparticle conjugates occurs with negative cooperativity; i.e., each binding event destabilizes subsequent binding events. DNA hybridization is thus an ever-changing function of the number of strands already
Monica Olvera de la Cruz +6 more
openaire +4 more sources
Single-molecule tracking of the transcription cycle by sub-second RNA detection
eLife, 2014 Transcription is an inherently stochastic, noisy, and multi-step process, in which fluctuations at every step can cause variations in RNA synthesis, and affect physiology and differentiation decisions in otherwise identical cells. However, it has been an
Zhengjian Zhang +4 more
doaj +1 more source
Sensors, 2020 A personal glucose meter (PGM)-based method for quantitative detection of a urinary nucleic acid biomarker in prostate cancer screening, the so-called PCA3, is reported herein.
Clara Abardía-Serrano +3 more
doaj +1 more source
Molecular structure and interactions of nucleic acid components in nanopaticles: ab initio calculations [PDF]
Ukrainian Journal of Physics, 2012, Vol. 57, no. 7, pp. 723-731, 2012 Self-associates of nucleic acid components (stacking trimers and tetramers of the base pairs of nucleic acids) and short fragments of nucleic acids are nanoparticles (linear sizes of these particles are more than 10 A. Modern quantum-mechanical methods and softwares allow one to perform ab initio calculations of the systems consisting of 150-200 atoms ...
arxiv
MethodsX, 2019 A fluorescence in situ hybridization (FISH) protocol was developed for nematodes in which nucleic acid probes are introduced within the organism via electroporation.
Casey L. Ruark-Seward +2 more
doaj
Impedimetric Sensing of Factor V Leiden Mutation by Zip Nucleic Acid Probe and Electrochemical Array
Biosensors, 2020 A carbon nanofiber enriched 8-channel screen-printed electrochemical array was used for the impedimetric detection of SNP related to Factor V Leiden (FV Leiden) mutation, which is the most common inherited form of thrombophilia.
Arzum Erdem, Ece Eksin
doaj +1 more source
Secondary structure formation of homopolymeric single-stranded nucleic acids including force and loop entropy: implications for DNA hybridization [PDF]
arXiv, 2011 Loops are essential secondary structure elements in folded DNA and RNA molecules and proliferate close to the melting transition. Using a theory for nucleic acid secondary structures that accounts for the logarithmic entropy c ln m for a loop of length m, we study homopolymeric single-stranded nucleic acid chains under external force and varying ...
arxiv
Analytical Chemistry, 2010 We identify and investigate several critical parameters in the fabrication of single-stranded DNA conjugated poly(ethylene glycol) (PEG) microparticles based on replica molding (RM) for highly uniform and robust nucleic acid hybridization assays.
Christina L. Lewis +4 more
semanticscholar +1 more source
Detection of Circovirus in Foxes with Meningoencephalitis, United Kingdom, 2009–2013
Emerging Infectious Diseases, 2015 A fox circovirus was identified in serum samples from foxes with unexplained neurologic signs by using viral metagenomics. Fox circovirus nucleic acid was localized in histological lesions of the cerebrum by in situ hybridization. Viruses from the family
Steve Bexton +11 more
doaj +1 more source