Results 111 to 120 of about 48,779 (251)

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

open access: yesAdvanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu   +7 more
wiley   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

open access: yesAdvanced Science, EarlyView.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li   +6 more
wiley   +1 more source

Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening

open access: yesAdvanced Science, EarlyView.
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu   +11 more
wiley   +1 more source

Recent Developments in Nanoparticle‐Hydrogel Hybrid Materials for Controlled Release

open access: yesAdvanced Science, EarlyView.
This review highlights recent advances in nanoparticle–hydrogel hybrid materials for controlled drug delivery. It explores diverse nanocarrier–hydrogel combinations, drug loading strategies, release mechanisms, and stimuli‐responsive behaviors. Emphasis is placed on the molecular interactions driving hybrid material performance, offering insights into ...
Yiping Fan   +8 more
wiley   +1 more source

Multifunctional NIR‐Triggered Nanozyme‐Based Microneedles for Synergistic Eradication of MRSA and Enhanced Wound Healing

open access: yesAdvanced Science, EarlyView.
The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian   +13 more
wiley   +1 more source

Characterization and Reuse of Lithium‐ion Battery Cathode Material Recovered Through a Bacterial Process

open access: yesAdvanced Energy Materials, EarlyView.
A sustainable bacteria‐based lithium‐ion battery cathode recycling method is optimized using engineering biology. The resulting biomineralized manganese carbonate species is found to be easily converted into an electrode material, via simple calcination.
Virginia Echavarri‐Bravo   +4 more
wiley   +1 more source

Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives

open access: yesAggregate, EarlyView.
Triterpenoids serve as both exceptional molecular motifs for supramolecular assembly and versatile therapeutic agents, offering broad biological functions to improve health outcomes and enhance treatment efficacy. This review comprehensively summarizes recent advances in triterpenoid‐based supramolecular systems, including their roles as functional ...
Jie Zhong   +3 more
wiley   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

open access: yesAdvanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee   +3 more
wiley   +1 more source

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