Results 1 to 10 of about 1,716 (122)
Uridine release during aminopyridine-induced epilepsy
Neurobiology of Disease, 2004 Uridine, like adenosine, is released under sustained depolarization and it can inhibit hippocampal neuronal activity, suggesting that uridine may be released during seizures and can be involved in epileptic mechanisms.In an in vivo microdialysis study ...
Andrea Slézia +2 more
exaly +3 more sources
Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice [PDF]
PLoS ONE, 2016 Uridine is a pyrimidine nucleoside that exerts restorative functions in tissues under stress. Short-term co-administration of uridine with multiple unrelated drugs prevents drug-induced liver lipid accumulation.
Yasuyo Urasaki +2 more
exaly +2 more sources
Indispensable residue for uridine binding in the uridine-cytidine kinase family
Biochemistry and Biophysics Reports, 2017 Uridine-cytidine kinase (UCK), including human UCK2, are a family of enzymes that generally phosphorylate both uridine and cytidine. However, UCK of Thermus thermophilus HB8 (ttCK) phosphorylates only cytidine.
Fumiaki Tomoike +5 more
doaj +3 more sources
Antioxidants, 2022 The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear.
Rong Xu +7 more
doaj +1 more source
Hospital Pharmacy, 2016 Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing ...
Cada, Dennis J +3 more
openaire +3 more sources
RSC Advances, 2022 The palladium-catalyzed oxidative C–H olefinations of uridine, deoxyuridine, uridine monophosphate and uridine analogues are reported herein.
Qin Zhao +6 more
openaire +2 more sources
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020 INTRODUCTION We examined associations between nutritional biomarkers and clinical progression in individuals with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD)‐type dementia.
Francisca A. deLeeuw +14 more
doaj +1 more source
A Treatable Genetic Disease Caused by CAD Mutation
Frontiers in Pediatrics, 2022 Type 50 early infantile epileptic encephalopathy, or EIEE-50 for short, is an autosomal recessive genetic disorder resulting from CAD mutations. So far, little has been reported on the disease.
Xia Peng +8 more
doaj +1 more source
Honey as Source of Nitrogen Compounds: Aromatic Amino Acids, Free Nucleosides and Their Derivatives
Molecules, 2020 The content of selected major nitrogen compounds including nucleosides and their derivatives was evaluated in 75 samples of seven varieties of honey (heather, buckwheat, black locust, goldenrod, canola, fir, linden) by targeted ultra-high performance ...
Piotr M. Kuś
doaj +1 more source
Uridine metabolism in HIV-1-infected patients: effect of infection, of antiretroviral therapy and of HIV-1/ART-associated lipodystrophy syndrome. [PDF]
PLoS ONE, 2010 BackgroundUridine has been advocated for the treatment of HIV-1/HAART-associated lipodystrophy (HALS), although its metabolism in HIV-1-infected patients is poorly understood.MethodsPlasma uridine concentrations were measured in 35 controls and 221 HIV-1-
Pere Domingo +14 more
doaj +1 more source