Results 31 to 40 of about 78,517 (164)
Unexpected Seven-Membered Ring Formation for Muraymycin-Type Nucleoside-Peptide Antibiotics
Molbank, 2020 Naturally occurring nucleoside-peptide antibiotics such as muraymycins or caprazamycins are of major interest for the development of novel antibacterial agents.
Kristin Leyerer +2 more
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Anti-Hepatitis C Virus Activity of Uridine Derivatives of 2-Deoxy Sugars
Molecules, 2018 Hepatitis C virus (HCV), the etiological agent of the most common and dangerous diseases of the liver, is a major health problem worldwide. Despite many attempts, there is still no vaccine available.
Ewelina Krol +3 more
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Case Report: Rapid Treatment of Uridine-Responsive Epileptic Encephalopathy Caused by CAD Deficiency
Frontiers in Pharmacology, 2020 We present two unrelated Chinese patients with CAD deficiency manifesting with a triad of infantile-onset psychomotor developmental delay with regression, drug-refractory epilepsy, and anaemia with anisopoikilocytosis.
Ling Zhou +10 more
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陆军军医大学学报Objective Retinitis pigmentosa (RP) exhibits complex genetic heterogeneity, and the downstream pathogenic mechanisms underlying different etiologies remain unclear.
MO Lingyue, CHA Zhe
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Beilstein Journal of Organic Chemistry, 2017 The 5’-alkynylation of uridine-derived aldehydes is described. The addition of alkynyl Grignard reagents on the carbonyl group is significantly influenced by the 2’,3’-di-O-protecting groups (R1): O-alkyl groups led to modest diastereoselectivities (65 ...
Raja Ben Othman +4 more
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Animal Nutrition, 2023 Carbohydrates have a protein sparing effect, but long-term feeding of a high-carbohydrate diet (HCD) leads to metabolic disorders due to the limited utilization efficiency of carbohydrates in fish.
Nan-Nan Zhou +8 more
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Uludağ Üniversitesi Tıp Fakültesi DergisiThe present study aimed to investigate the effects of uridine and the uridine nucleotides uridine-5’-monophosphate (UMP), uridine-5’-diphosphate (UDP) and uridine-5’-triphosphate (UTP) at different concentrations (1, 10 and 100 μM) on cell viability and ...
Diğdem Yöyen Ermiş +4 more
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Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases
Frontiers in PhysiologyUridine is a pyrimidine nucleoside found in plasma and cerebrospinal fluid with a concentration higher than the other nucleosides. As a simple metabolite, uridine plays a pivotal role in various biological processes. In addition to nucleic acid synthesis,
Yueyuan Yang +3 more
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Synthesis and cytotoxic activity of tri-acyl ester derivatives of uridine in breast cancer cells
Ars Pharmaceutica, 2016 Aims: Synthesize tri-acyl ester derivatives of uridine, and evaluate its cytotoxicity against breast cancer cells line. Methods: The tri-esterified uridine derivatives were obtained through Steglich esterification reaction by fatty and aromatic acids ...
Jhon Fernando Berrío Escobar +6 more
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Low Turnover of Soil Bacterial rRNA at Low Temperatures
Frontiers in Microbiology, 2020 Ribosomal RNA (rRNA) is used widely to investigate potentially active microorganisms in environmental samples, including soil microorganisms and other microbial communities that are subjected to pronounced seasonal variation in temperature. This raises a
Morten Dencker Schostag +8 more
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