Results 11 to 20 of about 1,716 (122)

Development of Diversified Methods for Chemical Modification of the 5,6-Double Bond of Uracil Derivatives Depending on Active Methylene Compounds

Molecules, 2012
The reaction of 5-halogenouracil and uridine derivatives <strong>1</strong> and <strong>7</strong> with active methylene compounds under basic conditions produced diverse and selective C-C bond formation products by virtue of the ...
Kosaku Hirota, Hideo Inoue, Yoshinari Sawama, Yoshifumi Maki, Yasunari Monguchi, Yukio Kitade, Kanoko Ikawa, Yusuke Iida, Hironao Sajiki   +8 more
doaj   +1 more source

SYNTHESIS A NUMBER OF URIDINE DERIVATIVES AND STUDYING THEIR BIOLOGICAL ACTIVITY ON PATHOGENIC BACTERIA. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
یتضمن البحث تحضیر سلسلة من المرکبات بطریقة ازدواج املاح الدیازونیوم مع الیوردین. وتم التأکد من الصیغ الترکیبیة للمرکبات المحضرة بدراسة اطیاف الاشعة فوق البنفسجیة (U.V) واطیاف الاشعة تحت الحمراء(I.R) والتحلیل الدقیق لعناصر الکاربون، الهیدروجین والنتروجین (
YOUSIF HINDY KHALAF, SALMAN ALI AHMED
doaj   +1 more source

URIDINE DIPHOSPHATE ACETYLGLUCOSAMINE

Journal of Biological Chemistry, 1953
Blanco y ...
Cabib, Enrico, Leloir, Luis Federico, Cardini, Carlos E.   +2 more
openaire   +3 more sources

Uridine Prevents Negative Effects of OXPHOS Xenobiotics on Dopaminergic Neuronal Differentiation

Cells, 2019
Neuronal differentiation appears to be dependent on oxidative phosphorylation capacity. Several drugs inhibit oxidative phosphorylation and might be detrimental for neuronal differentiation.
Eldris Iglesias, M. Pilar Bayona-Bafaluy, Alba Pesini, Nuria Garrido-Pérez, Patricia Meade, Paula Gaudó, Irene Jiménez-Salvador, Julio Montoya, Eduardo Ruiz-Pesini   +8 more
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mRNA Expression and Activity of Nucleoside Transporters in Human Hepatoma HepaRG Cells

Pharmaceutics, 2018
The HepaRG cell line is a highly differentiated human hepatoma cell line, displaying the expression of various drug transporters. However, functional expression of nucleoside transporters remains poorly characterized in HepaRG cells, although these ...
Abdullah Mayati, Amélie Moreau, Elodie Jouan, Marie Febvre-James, Claire Denizot, Yannick Parmentier, Olivier Fardel   +6 more
doaj   +1 more source

Identification of Major Antioxidant Compounds from the Edible Mushroom Basidiomycetes-X (Echigoshirayukidake)

Frontiers in Bioscience-Elite, 2022
Basidiomycetes-X, of which Japanese vernacular name is Echigoshirayukidake, is a local speciality mushroom found and cultivated in Japan that has been distributed as a precious cuisine material or as a functional food with medicinal properties ...
Toshio Sakamoto, Zhenshi Li, Ayaka Nishida, Asako Kadokawa, Takayuki Yoshida, Naoki Wada, Seiichi Matsugo, Yutaka Nakamura, Shinji Sato, Tetsuya Konishi   +9 more
doaj   +1 more source

From Formamide to RNA, the Path Is Tenuous but Continuous

Life, 2015
Reactions of formamide (NH2COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially
Samanta Pino, Judit E. Sponer, Giovanna Costanzo, Raffaele Saladino, Ernesto Di Mauro   +4 more
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An Open-label Randomized Crossover Study with Adaptive Design of the Pharmacokinetics and Bioequivalence of GP30121 and Ceraxon® Corrected for Endogenous Analyte Level

Разработка и регистрация лекарственных средств, 2023
Introduction. Citicoline is an endogenous nucleoside consisting of cytidine and choline linked by a diphosphate bridge that is involved in the synthesis of membrane phospholipids.
A. N. Arevefa, A. R. Dorotenko, S. M. Noskov, I. E. Makarenko, R. V. Drai, T. N. Komarov, O. A. Archakova, N. S. Bagaeva, I. E. Shokhin   +8 more
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A Patient With CAD Deficiency Responsive to Uridine and Literature Review

Frontiers in Neurology, 2020
CAD encodes a multifunctional enzyme involved in de novo pyrimidine biosynthesis, and pyrimidine can be alternatively recycled from uridine. Trio whole-exome sequencing identified CAD compound heterozygous mutations in a new male patient with global ...
Ling Zhou, Han Xu, Tianshuang Wang, Ye Wu   +3 more
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Uridine treatment protects against blood–brain barrier disruption in a rat model of Li-pilocarpine-induced status epilepticus

Frontiers in Neuroscience
IntroductionBlood–brain barrier (BBB) disruption is one of the most striking changes triggered by status epilepticus, which deserves specific attention in terms of novel treatment approaches targeting epileptogenesis.
Birnur Aydin, Busra Ocalan Esmerce, Aysen Cakir, Sueda Tuncak, Cansu Koc, Mehmet Cansev, Tulin Alkan   +6 more
doaj   +1 more source