Results 51 to 60 of about 74,197 (237)

Crystal structure of 5-(dibenzofuran-4-yl)-2′-deoxyuridine

Acta Crystallographica Section E: Crystallographic Communications, 2017
The molecule of the title compound, C21H18N2O6, has a bent rather than a linear conformation supported by three intramolecular C—H...O hydrogen bonds. The packing in the crystal lattice is largely determined by interactions between hydrogen atoms with ...
Vijay Gayakhe, Anant Ramakant Kapdi, Yulia Borozdina, Carola Schulzke   +3 more
doaj   +1 more source

Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement. [PDF]

PLoS ONE, 2011
Uridine is a therapy for hereditary orotic aciduria and is being investigated in other disorders caused by mitochondrial dysfunction, including toxicities resulting from treatment with nucleoside reverse transcriptase inhibitors in HIV. Historically, the
Melissa E Weinberg, Mark C Roman, Peyton Jacob, Michael Wen, Polly Cheung, Ulrich A Walker, Kathleen Mulligan, Morris Schambelan   +7 more
doaj   +1 more source

Synthesis of uridine derivatives

Communications, Faculty Of Science, University of Ankara Series B Chemistry and Chemical Engineering, 1992
2', 3'-0 isopropylidene-5-ammomethyl uridine was condensed with some aldehydes. in the şame time, reduçtion 44in situ” of the reaction products was achieved Ncvçrtheless, the resulting compounds showed to be unstable during chromatographic processes.
openaire   +2 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Lipidomic and transcriptomic profiles provide new insights into the triacylglycerol and glucose handling capacities of the Arctic fox

Frontiers in Veterinary Science
The Arctic fox (Vulpes lagopus) is a species indigenous to the Arctic and has developed unique lipid metabolism, but the mechanisms remain unclear.
Yuhang Zhu, Yuan Yuan, Huazhe Si, Huazhe Si, Songze Li, Fei Zhao, Ruina Mu, Zihan Lin, Xiaoxu Wang, Qiang Qiu, Chao Xu, Lele Ji, Zhipeng Li, Zhipeng Li   +13 more
doaj   +1 more source

Protective effect of uridine on atrial fibrillation: a Mendelian randomisation study

Scientific Reports, 2023
Uridine, a pyrimidine nucleoside, is crucial in the synthesis of metabolites. According to observational studies, a higher plasma uridine level is associated with a lower risk of atrial fibrillation (AF).
Xintian Xu, Xiaoyu Zhang, Shiyao Cheng, Qinglang Li, Cai Chen, Mao Ouyang   +5 more
doaj   +1 more source

Chemical Oxidation of Uridine Diphosphate-Glucose to Uridine Diphosphate-Glucuronic Acid [PDF]

Nature, 1961
THE importance of uronic acids in carbohydrate metabolism has only recently begun to be elucidated. The metabolism of inositol and ascorbate is known to involve uronic acid intermediates1,2, and nucleotide-bound glucuronic acid has been implicated in hyaluronic acid synthesis3.
B, JACOBSON, E A, DAVIDSON
openaire   +2 more sources

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

Anti-Inflammatory Responses Produced with Nippostrongylus brasiliensis-Derived Uridine via the Mitochondrial ATP-Sensitive Potassium Channel and Its Anti-Atherosclerosis Effect in an Apolipoprotein E Gene Knockout Mouse Model

Biomolecules
Atherosclerosis (AS) has become the leading cause of cardiovascular disease worldwide. Our previous study had observed that Nippostrongylus brasiliensis (Nb) infection or its derived products could inhibit AS development by inducing an anti-inflammatory ...
Yingshu Zhang, Xin Ding, Caiyi Yuan, Yougui Yang, Qiang Zhang, Jiakai Yao, Ying Zhang, Junhong Wang, Yang Dai   +8 more
doaj   +1 more source