Results 51 to 60 of about 78,517 (164)

Nucleotides Cytidine and Uridine Associated with Vitamin B12 vs B-Complex Vitamins in the Treatment of Low Back Pain: The NUBES Study

open access: yesJournal of Pain Research, 2020
Marco Antonio Naslausky Mibielli,1 Carlos Pereira Nunes,1,2 Henrique Goldberg,3 Luiz Buchman,2 Lisa Oliveira,4 Spyros GE Mezitis,5 Fernanda Wajnzstajn,6 Renato Kaufman,3 Rafael Nigri,7 Natasha Cytrynbaum,3 Karin Soares Cunha,8 Alessandra Santos,4 ...
Mibielli MAN   +17 more
doaj  

The predictive value of plasma uridine for type 2 diabetes and its atherosclerotic complications

open access: yesEndocrine Connections
Objective: Uridine might be a common link between pathological pathways in diabetes and cardiovascular diseases. This study aimed to investigate the predictive value of plasma uridine for type 2 diabetes (T2D) and T2D with atherosclerosis.
Yueyuan Yang   +3 more
doaj   +1 more source

Local Treatment of Hand-Foot Syndrome with Uridine/Thymidine: In Vitro Appraisal on a Human Keratinocyte Cell Line HaCaT

open access: yesThe Scientific World Journal, 2012
5-fluorouracil (5-FU) is one of the most commonly used antineoplastic drugs in the anticancer therapy. The hand-foot (HF) syndrome (palmar-plantar erythrodysesthesia) is an adverse effect frequently related to long-term i.v. administration of 5-FU or its
J. Hartinger   +5 more
doaj   +1 more source

Pharmacological targets of SGLT2 inhibition on prostate cancer mediated by circulating metabolites: a drug-target Mendelian randomization study

open access: yesFrontiers in Pharmacology
BackgroundThe relationship between sodium-glucose cotransporter 2 (SGLT2) inhibitors and prostate cancer is still unknown. Although these inhibitors can influence tumor glycolysis, the underlying mechanism requires further exploration.MethodsA two-sample
Yilong Lin   +10 more
doaj   +1 more source

Antifungal activity of the nucleoside mimetic 5-fluorouridine against Candidozyma auris and Candida species

open access: yesAntimicrobial Agents and Chemotherapy
The emergence of multidrug-resistant Candidozyma auris has created an urgent need for antifungals with novel mechanisms of action. We screened 121 nucleoside and nucleobase derivatives against C.
Bharath Reddy Boya   +3 more
doaj   +1 more source

A novel combination therapy with Uridine and Praziquantel effectively alleviates schistosomiasis-induced hepatic fibrosis through promoting adipogenic differentiation.

open access: yesPLoS Pathogens
Schistosomiasis-induced hepatic fibrosis, a consequence of egg-induced granulomatous lesions, remains untreated by current drugs. Therefore, the development of novel antifibrosis drugs is of paramount importance.
Xiangyu Zhou   +10 more
doaj   +1 more source

Nucleotide Metabolic Reprogramming in Sepsis: From Immune-Cell Fate to Organ Injury and Precision Therapeutics

open access: yesJournal of Inflammation Research
Chun Wang,1 Fu Shuying,1 Jin Jing,2 Fang Fuquan,1 Jie Huang11Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Zhejiang Center for Clinical Laboratory ...
Wang C   +4 more
doaj  

ENZYMATIC SYNTHESIS OF URIDINE DIPHOSPHATE XYLOSE AND URIDINE DIPHOSPHATE ARABINOSE [PDF]

open access: yesProceedings of the National Academy of Sciences, 1956
V, Ginsburg, E F, Neufeld, W Z, Hassid
openaire   +2 more sources

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