Results 211 to 220 of about 58,888 (249)
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Entamoeba histolytica: Nucleic acid precursors affecting axenic growth
Experimental Parasitology, 1980Abstract Treatment of Panmede and Trypticase, in water, with activated carbon and subsequently combining the filtered solution with glucose, cysteine, salts, serum and vitamins results in a medium depleted in the nucleic acid precursors required to sustain a high level of growth of axenic Entamoeba histolytica.
Richard E Reeves
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Requirements ofAcholeplasma laidlawii A, strain LA 1, for nucleic acid precursors
Folia Microbiologica, 1974The requirements for nucleic acid precursors byAcholeplasma laidlawii type A, strain LA 1, were studied. The absence of a requirement for ribose or deoxyribose and the interconvertibility of uridine and cytidine contrasts with previously reported results with strain pG 8.
B Liska, P F Smith
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Effect of 5-fluorouracil on the incorporation of precursors into nucleic acid pyrimidines
Archives of Biochemistry and Biophysics, 1957Maxwell L Eidinoff, M L Eidinoff
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The Role of the Membrane in the Utilization of Nucleic Acid Precursor
CRC Critical Reviews in Biochemistry, 1974(1974). The Role of the Membrane in the Utilization of Nucleic Acid Precursor. CRC Critical Reviews in Biochemistry: Vol. 2, No. 2, pp. 259-310.
Joy Hochstadt, B. Magasanik
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Uptakein Vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells
The Journal of Membrane Biology, 1975Zajdela ascitic hepatoma cells are shown to take up pyrimidine bases at much lower rates than obtained in slices from normal rat liver. The rates of uptake of adenine and uridine by the Zajdela cells are, however, as high as in the slices. Like the slices, again, the Zajdela cells take up E.
P M, Bhargava +3 more
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Inhibitory effects of orotate on precursor incorporation into nucleic acids
Chemico-Biological Interactions, 1990The influence of orotic acid on the incorporation of precursors into nucleic acids was studied in mice and rats and in isolated cells. In vivo, orotate levels were modified by two diets which are known to increase the rate of pyrimidine nucleotide synthesis in rat liver.
M A, Lea, A, Luke, A, Assad, S, Ayyala
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Metabolism of caffeine to nucleic acid precursors in mammalian cells
Mutation Research, 1976Caffeine is rapidly metabolized in human and mouse cells in culture by de-methylation: within 1-3 h of exposure to millimolar concentrations of labeled caffeine, more than 90% of the pool consists of labeled products of metabolism and less than 10% is still caffeine. The methyl groups seem to be transferred and used in the de novo synthesis of thymine,
R, Goth, J E, Cleaver
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Synthesis of phage-precursor nucleic acid in the presence of chloramphenicol
Virology, 1957If chloramphenicol is added to a bacterial culture infected with T2 some minutes earlier, synthesis of phage nucleic acid proceeds with very little concomitant protein synthesis. If chloramphenicol is subsequently removed, phage particles promptly start to form, and the phosphorus of nucleic acid synthesized during the chloramphenicol period enters ...
A D, HERSHEY, N E, MELECHEN
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Peptide Nucleic Acids Targeted to the Amyloid Precursor Protein
Journal of Molecular Neuroscience, 2003The depositing in brain of amyloid beta peptide (Abeta), which is formed by the cleavage of amyloid precursor protein (APP), is likely an etiologic factor in Alzheimer's disease (AD). Of the different forms of Abeta, Abeta(1-42) causes fibril formation and increases aggregation at elevated levels, which can lead to neuronal death.
Beth M, McMahon +5 more
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Adenosylmethionine as a Precursor for Nucleic Acids Modification
1980Adenosylmethionine (Ado-Met) is the most important donor of alkyl groups, which are transferred from the sulfonium pole to a variety of nucleophilic molecular species within the cell1. The reaction involves nucleophilic attack to one of the three carbon atoms adjacent to the electron-deficient trivalent sulfur (see Figure 1) and is catalyzed by ...
SALVATORE, FRANCESCO +5 more
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