Multiple sequence alignments of partially coding nucleic acid sequences [PDF]
BMC Bioinformatics, 2005 Background High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data.
Fried Claudia +3 more
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CFSP: a collaborative frequent sequence pattern discovery algorithm for nucleic acid sequence classification [PDF]
PeerJ, 2020 Background Conserved nucleic acid sequences play an essential role in transcriptional regulation. The motifs/templates derived from nucleic acid sequence datasets are usually used as biomarkers to predict biochemical properties such as protein binding ...
He Peng
doaj +3 more sources
CRISPR-induced DNA reorganization for multiplexed nucleic acid detection [PDF]
Nature Communications, 2023 Nucleic acid sensing involving CRISPR technologies is powerful but has certain limitations, such as PAM sequence requirements and limited multiplexing.
Margot Karlikow +15 more
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Nucleic Acid Ligands Based on Carbohydrates [PDF]
CHIMIA, 1996 Sequence-specific nucleic acid ligands are important tools in chemistry and molecular biology and are thought to possess a considerable pharmaceutical potential. An overview of the structurally and mechanistically diverse approaches in the field
Jürg Hunziker
doaj +5 more sources
Nucleic Acid Sequence-Based Amplification using molecular beacons for quantification of enterovirus RNA [PDF]
Microbiologia Medica, 2011 Quantificazione dell’enterovirus RNA mediante Nucleic Acid Sequence-Based Amplification utilizzando sonde molecular ...
Francesca Sidoti +5 more
doaj +4 more sources
Enlarged Similarity of Nucleic Acid Sequences [PDF]
DNA Research, 1996 The concept of nucleic acid sequence base alternations is presented. The number of base alterations for the sequences of different length is established. The definition of "enlarged similarity" of nucleic acids sequences on the basis of sequence base alterations is introduced.
Maria A. Korotkova, Eugene V. Korotkov
openaire +4 more sources
Ligation with nucleic acid sequence-based amplification. [PDF]
J Mol Diagn, 2012 This work presents a novel method for detecting nucleic acid targets using a ligation step along with an isothermal, exponential amplification step. We use an engineered ssDNA with two variable regions on the ends, allowing us to design the probe for optimal reaction kinetics and primer binding. This two-part probe is ligated by T4 DNA Ligase only when
Ong C +5 more
europepmc +4 more sources
Identification of nucleic acid binding sites on translin-associated factor X (TRAX) protein. [PDF]
PLoS ONE, 2012 Translin and TRAX proteins play roles in very important cellular processes such as DNA recombination, spatial and temporal expression of mRNA, and in siRNA processing.
Gagan Deep Gupta, Vinay Kumar
doaj +6 more sources
FBPP: software to design PCR primers and probes for nucleic acid base detection of foodborne pathogens [PDF]
Scientific ReportsFoodborne pathogens can be found in various foods, and it is important to detect foodborne pathogens to provide a safe food supply and to prevent foodborne diseases.
Mohamed A. Soliman +4 more
doaj +3 more sources