Multiple sequence alignments of partially coding nucleic acid sequences [PDF]
Background High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data.
Fried Claudia+3 more
doaj +10 more sources
CFSP: a collaborative frequent sequence pattern discovery algorithm for nucleic acid sequence classification [PDF]
Background Conserved nucleic acid sequences play an essential role in transcriptional regulation. The motifs/templates derived from nucleic acid sequence datasets are usually used as biomarkers to predict biochemical properties such as protein binding ...
He Peng
doaj +3 more sources
Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure [PDF]
A dot hybridization method is presented for rapidly determining the relative concentrations of nucleic acids in a mixture, as well as the extent of sequence homology between related RNA or DNA species.
Fotis C. Kafatos+2 more
openalex +2 more sources
Rapid and Sensitive Isothermal Detection of Nucleic-acid Sequence by Multiple Cross Displacement Amplification. [PDF]
We have devised a novel amplification strategy based on isothermal strand-displacement polymerization reaction, which was termed multiple cross displacement amplification (MCDA).
Wang Y+8 more
europepmc +2 more sources
Constrained Multistate Sequence Design for Nucleic Acid Reaction Pathway Engineering [PDF]
We describe a framework for designing the sequences of multiple nucleic acid strands intended to hybridize in solution via a prescribed reaction pathway.
Dirks, Robert M.+4 more
core +4 more sources
Human liver apolipoprotein B-100 cDNA: complete nucleic acid and derived amino acid sequence.
Human apolipoprotein B-100 (apoB-100), the ligand on low density lipoproteins that interacts with the low density lipoprotein receptor and initiates receptor-mediated endocytosis and low density lipoprotein catabolism, has been cloned, and the complete ...
S W Law+6 more
openalex +2 more sources
Nucleic Acid Sequence Design via Efficient Ensemble Defect Optimization [PDF]
We describe an algorithm for designing the sequence of one or more interacting nucleic acid strands intended to adopt a target secondary structure at equilibrium.
Pierce, Niles A.+2 more
core +2 more sources
Diagnostic Value of Monitoring Human Cytomegalovirus Late pp67 mRNA Expression in Renal-Allograft Recipients by Nucleic Acid Sequence-Based Amplification [PDF]
The diagnostic value of monitoring human cytomegalovirus (HCMV) late pp67 mRNA expression by nucleic acid sequence-based amplification (NASBA) after renal-allograft transplantation was evaluated.
Marinus J. Blok+8 more
openalex +2 more sources
Development of nucleic acid-based RAA test strip assay for the rapid detection of foot-and-mouth disease virus [PDF]
Foot-and-mouth disease virus (FMDV) causes blister-like lesions in animals, leading to significant economic losses in animal husbandry. Accurate and rapid detection of FMD is crucial for effective prevention and control.
Wenxian Chen+10 more
doaj +2 more sources
Sequence-based analysis and prediction are fundamental bioinformatic tasks that facilitate understanding of the sequence(-structure)-function paradigm for DNAs, RNAs and proteins.
Zhen Chen+11 more
semanticscholar +1 more source