Results 141 to 150 of about 1,295,417 (401)

FBPP: software to design PCR primers and probes for nucleic acid base detection of foodborne pathogens

open access: yesScientific Reports
Foodborne pathogens can be found in various foods, and it is important to detect foodborne pathogens to provide a safe food supply and to prevent foodborne diseases.
Mohamed A. Soliman   +4 more
doaj   +1 more source

Energy landscapes and dynamics of xylo-nucleic acids [PDF]

open access: yesarXiv, 2019
Artificial analogues of the natural nucleic acids have attracted recent interest as a diverse class of information storage molecules capable of self-replication. In the present study, we use the computational potential energy landscape framework to investigate the structural and dynamical properties of xylo- and deoxyxylo-nucleic acids (XyNA and dXyNA),
arxiv  

Visualising single molecules of HIV-1 and miRNA nucleic acids [PDF]

open access: yes, 2013
BackgroundThe scarcity of certain nucleic acid species and the small size of target sequences such as miRNA, impose a significant barrier to subcellular visualization and present a major challenge to cell biologists.
Hirst, Bevan   +9 more
core   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Diacylglycerol Acyltransferase Sequences and Related Methods [PDF]

open access: yes, 2013
Isolated nucleic acid and amino acid sequences encoding a diacylglycerol acyltransferase 2 (DGAT2) polypeptide are provided. Vectors and transgenic cells that include a nucleic acid sequence encoding a DGAT2 polypeptide are also described.
Hatanaka, Tomoko   +2 more
core   +1 more source

Enzyme-Free Translation of DNA into Sequence-Defined Synthetic Polymers Structurally Unrelated to Nucleic Acids [PDF]

open access: yes, 2015
The translation of DNA sequences into corresponding biopolymers enables the production, function, and evolution of the macromolecules of life. In contrast, methods to generate sequence-defined synthetic polymers with similar levels of control have ...
Hili, Ryan, Liu, David R., Niu, Jia
core   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Buckyballs conjugated with nucleic acid sequences identifies microorganisms in live cell assays

open access: yesJournal of Nanobiotechnology, 2017
Background Rapid identification of bacteria can play an important role at the point of care, evaluating the health of the ecosystem, and discovering spatiotemporal distributions of a bacterial community.
Qingsu Cheng, Bahram Parvin
doaj   +1 more source

APPLICATION OF NUCLEIC ACID SEQUENCE-BASED AMPLIFICATION FOR THE DETECTION OF VIABLE FOODBORNE PATHOGENS: PROGRESS AND CHALLENGES

open access: yes, 2006
Nucleic acid sequence-based amplification (NASBA) is a sensitive transcription-based amplification system that uses a battery of three enzymes (avian myeloblastosis virus reverse transcriptase, RNase H and T7 RNA polymerase) leading to a main ...
D. Rodríguez-Lázaro   +3 more
semanticscholar   +1 more source

Detection of piscine nodaviruses by real-time nucleic acid sequence based amplification (NASBA).

open access: yesDiseases of Aquatic Organisms, 2004
Nucleic acid sequence based amplification (NASBA) is an isothermal nucleic acid amplification procedure based on target-specific primers and probes, and the co-ordinated activity of 3 enzymes: AMV reverse transcriptase, RNase H, and T7 RNA polymerase. We
WG Starkey   +5 more
semanticscholar   +1 more source

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