A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi+5 more
wiley +1 more source
Regulatory pattern Identification in nucleic acid sequences [PDF]
John R. Sadler+2 more
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An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D [PDF]
Background: The phenotypic effects of sequence variations in protein-coding regions come about primarily via their effects on the resulting structures, for example by disrupting active sites or affecting structural stability.
Baresic, A+7 more
core
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz+3 more
wiley +1 more source
The complete nucleic acid sequence of gene segment 3 of the IDIR strain of group B rotavirus [PDF]
Shigehiro Sato+2 more
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A Family of Developmentally Excised DNA Elements in \u3cem\u3eTetrahymena\u3c/em\u3e is under Selective Pressure to Maintain an Open Reading Frame Encoding an Integrase-Like Protein [PDF]
Tlr1 is a member of a family of ~20-30 DNA elements that undergo developmentally regulated excision during formation of the macronucleus in the ciliated protozoan Tetrahymena.
Gershan, Jill A., Karrer, Kathleen M.
core +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
DETERMINATION OF BASE SEQUENCE IN NUCLEIC ACIDS WIT THE ELECTRON MICROSCOPE: VISIBILITY OF A MARKER
M Beer, Evangelos N. Moudrianakis
openalex +1 more source
Nomenclature Committee for the International Union of Biochemistry (NC-IUB). Nomenclature for incompletely specified bases in nucleic acid sequences. Recommendations 1984. [PDF]
openalex +1 more source