Nucleic Acid Sequence Design via Efficient Ensemble Defect Optimization [PDF]
Journal of Computational Chemistry, 2011 We describe an algorithm for designing the sequence of one or more interacting nucleic acid strands intended to adopt a target secondary structure at equilibrium.
Pierce, Niles A. +2 more
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Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure [PDF]
Nucleic Acids Research, 1979 Fotis C. Kafatos +2 more
openalex +2 more sources
Human liver apolipoprotein B-100 cDNA: complete nucleic acid and derived amino acid sequence.
Proceedings of the National Academy of Sciences of the United States of America, 1986 S W Law +6 more
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Rapid and Sensitive Isothermal Detection of Nucleic-acid Sequence by Multiple Cross Displacement Amplification. [PDF]
Sci Rep, 2015 We have devised a novel amplification strategy based on isothermal strand-displacement polymerization reaction, which was termed multiple cross displacement amplification (MCDA).
Wang Y +8 more
europepmc +2 more sources
Nucleic Acids Research, 2021 Sequence-based analysis and prediction are fundamental bioinformatic tasks that facilitate understanding of the sequence(-structure)-function paradigm for DNAs, RNAs and proteins.
Zhen Chen +11 more
semanticscholar +1 more source
Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA
Nature Methods, 2023 Protein–RNA and protein–DNA complexes play critical roles in biology. Despite considerable recent advances in protein structure prediction, the prediction of the structures of protein–nucleic acid complexes without homology to known complexes is a ...
M. Baek +5 more
semanticscholar +1 more source
Argonaute protein-based nucleic acid detection technology
Frontiers in Microbiology, 2023 It is vital to diagnose pathogens quickly and effectively in the research and treatment of disease. Argonaute (Ago) proteins are recently discovered nucleases with nucleic acid shearing activity that exhibit specific recognition properties beyond CRISPR ...
Zhiyun Wu +3 more
doaj +1 more source
Sequence-Specific Sensing of Nucleic Acids [PDF]
Trends in Immunology, 2017 Innate immune cells are endowed with many nucleic acid receptors, but the role of sequence in the detection of foreign organisms remains unclear. Can sequence patterns influence recognition? In addition, how can we infer those patterns from sequence data?
Benjamin Greenbaum +2 more
openaire +3 more sources
Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
Pharmaceutics, 2020 In nature, genomes have been optimized by the evolution of their nucleic acid sequences. The design of peptide-like carriers as synthetic sequences provides a strategy for optimizing multifunctional targeted nucleic acid delivery in an iterative process.
Yanfang Wang, Ernst Wagner
doaj +1 more source
Analysis of Nucleotide Sequences Similarity and Protein Prediction of Some Resistance Genes in Escherichia coli Isolated from Iraqi Patients with Urinary Tract Infections [PDF]
Archives of Razi Institute, 2022 Antibiotic resistance leads to a dramatic increase in the morbidity and mortality caused by infectious diseases. Even though estimates vary widely, the economic cost of antimicrobial-resistant bacteria is on a rise.
R Kadhim Mohammed, A Attallah Ibrahim
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