Results 11 to 20 of about 376,743 (310)
CFSP: a collaborative frequent sequence pattern discovery algorithm for nucleic acid sequence classification [PDF]
PeerJ, 2020 Background Conserved nucleic acid sequences play an essential role in transcriptional regulation. The motifs/templates derived from nucleic acid sequence datasets are usually used as biomarkers to predict biochemical properties such as protein binding ...
He Peng
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NASCUP: Nucleic Acid Sequence Classification by Universal Probability [PDF]
IEEE Access, 2021 Nucleic acid sequence classification is a fundamental task in the field of bioinformatics. Due to the increasing amount of unlabeled nucleotide sequences, fast and accurate classification of them on a large scale has become crucial.
Sunyoung Kwon +5 more
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Ligation with nucleic acid sequence-based amplification. [PDF]
J Mol Diagn, 2012 This work presents a novel method for detecting nucleic acid targets using a ligation step along with an isothermal, exponential amplification step. We use an engineered ssDNA with two variable regions on the ends, allowing us to design the probe for optimal reaction kinetics and primer binding. This two-part probe is ligated by T4 DNA Ligase only when
Ong C +5 more
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Microbiologia Medica, 2011 Quantificazione dell’enterovirus RNA mediante Nucleic Acid Sequence-Based Amplification utilizzando sonde molecular ...
Francesca Sidoti +5 more
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ReAlign-N: an integrated realignment approach for multiple nucleic acid sequence alignment, combining global and local realignments. [PDF]
NAR Genom BioinformZhai Y, Zhou T, Wei Y, Zou Q, Wang Y.
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Nature Biotechnology, 2019 The genotype (structural genomics) of non-cellular entities, single cells and multicellular organisms determines their phenotype, which in turn can be potentially beneficial or dangerous from an anthropomorphic and biotechnological point of view. The sequencing of nucleic acids was accomplished after many trials, using different methods that were ...
Dorado, Gabriel +4 more
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Protein-Based Anchoring Methods for Nucleic Acid Detection in Lateral Flow Format Assays
Micromachines, 2023 The use of lateral flow assays to detect nucleic acid targets has many applications including point-of-care diagnostics, environmental monitoring, and food safety.
Kira Hallerbach +6 more
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Biosensors, 2021 Enteroviruses are ubiquitous mammalian pathogens that can produce mild to life-threatening disease. We developed a multimodal, rapid, accurate and economical point-of-care biosensor that can detect nucleic acid sequences conserved amongst 96% of all ...
Veeren M. Chauhan +5 more
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Argonaute protein-based nucleic acid detection technology
Frontiers in Microbiology, 2023 It is vital to diagnose pathogens quickly and effectively in the research and treatment of disease. Argonaute (Ago) proteins are recently discovered nucleases with nucleic acid shearing activity that exhibit specific recognition properties beyond CRISPR ...
Zhiyun Wu +3 more
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Optimization of Nucleic Acid Sequences [PDF]
Biophysical Journal, 2000 Base sequence influences the structure, mechanics, dynamics, and interactions of nucleic acids. However, studying all possible sequences for a given fragment leads to a number of base combinations that increases exponentially with length. We present here a novel methodology based on a multi-copy approach enabling us to determine which base sequence ...
Lafontaine, Ingrid, Lavery, Richard
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