Results 11 to 20 of about 694,635 (336)

CFSP: a collaborative frequent sequence pattern discovery algorithm for nucleic acid sequence classification [PDF]

open access: yesPeerJ, 2020
Background Conserved nucleic acid sequences play an essential role in transcriptional regulation. The motifs/templates derived from nucleic acid sequence datasets are usually used as biomarkers to predict biochemical properties such as protein binding ...
He Peng
doaj   +3 more sources

Enlarged Similarity of Nucleic Acid Sequences [PDF]

open access: goldDNA Research, 1996
The concept of nucleic acid sequence base alternations is presented. The number of base alterations for the sequences of different length is established. The definition of "enlarged similarity" of nucleic acids sequences on the basis of sequence base alterations is introduced.
Eugene Korotkov, Maria A. Korotkova
openalex   +4 more sources

Multiple sequence alignments of partially coding nucleic acid sequences [PDF]

open access: yesBMC Bioinformatics, 2005
Background High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data.
Fried Claudia   +3 more
doaj   +5 more sources

Ligation with nucleic acid sequence-based amplification. [PDF]

open access: yesJ Mol Diagn, 2012
This work presents a novel method for detecting nucleic acid targets using a ligation step along with an isothermal, exponential amplification step. We use an engineered ssDNA with two variable regions on the ends, allowing us to design the probe for optimal reaction kinetics and primer binding. This two-part probe is ligated by T4 DNA Ligase only when
Ong C   +5 more
europepmc   +4 more sources

Development of nucleic acid-based RAA test strip assay for the rapid detection of foot-and-mouth disease virus [PDF]

open access: yesFrontiers in Veterinary Science
Foot-and-mouth disease virus (FMDV) causes blister-like lesions in animals, leading to significant economic losses in animal husbandry. Accurate and rapid detection of FMD is crucial for effective prevention and control.
Wenxian Chen   +10 more
doaj   +2 more sources

Nucleic-Acid Sequencing [PDF]

open access: yesNature Biotechnology, 2019
Peer ...
Dorado, Gabriel   +4 more
openaire   +5 more sources

Protein-Based Anchoring Methods for Nucleic Acid Detection in Lateral Flow Format Assays

open access: yesMicromachines, 2023
The use of lateral flow assays to detect nucleic acid targets has many applications including point-of-care diagnostics, environmental monitoring, and food safety.
Kira Hallerbach   +6 more
doaj   +1 more source

Gold–Oligonucleotide Nanoconstructs Engineered to Detect Conserved Enteroviral Nucleic Acid Sequences

open access: yesBiosensors, 2021
Enteroviruses are ubiquitous mammalian pathogens that can produce mild to life-threatening disease. We developed a multimodal, rapid, accurate and economical point-of-care biosensor that can detect nucleic acid sequences conserved amongst 96% of all ...
Veeren M. Chauhan   +5 more
doaj   +1 more source

NASCUP: Nucleic Acid Sequence Classification by Universal Probability

open access: yesIEEE Access, 2021
Nucleic acid sequence classification is a fundamental task in the field of bioinformatics. Due to the increasing amount of unlabeled nucleotide sequences, fast and accurate classification of them on a large scale has become crucial.
Sunyoung Kwon   +5 more
doaj   +1 more source

Optimization of Nucleic Acid Sequences [PDF]

open access: yesBiophysical Journal, 2000
Base sequence influences the structure, mechanics, dynamics, and interactions of nucleic acids. However, studying all possible sequences for a given fragment leads to a number of base combinations that increases exponentially with length. We present here a novel methodology based on a multi-copy approach enabling us to determine which base sequence ...
Ingrid Lafontaine, Richard Lavery
openaire   +3 more sources

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