Advanced Healthcare Materials, EarlyView.In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu +5 more
wiley +1 more source
A general procedure for locating and analyzing protein-binding sequence motifs in nucleic acids [PDF]
, 1998 Michael C. O’Neill
openalex +1 more source
SD-chip enabled quantitative detection of HIV RNA using digital nucleic acid sequence-based amplification (dNASBA). [PDF]
Lab Chip, 2018 Wang J +12 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
High-density multiplex detection of nucleic acid sequences: oligonucleotide ligation assay and sequence-coded separation [PDF]
, 1998 P. D. Grossman +8 more
openalex +1 more source
Development of a Quantitative Real-time Nucleic Acid Sequence based Amplification (NASBA) Assay for Early Detection of Apple scar skin viroid. [PDF]
Plant Pathol J, 2019 Heo S, Kim HR, Lee HJ.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah +9 more
wiley +1 more source
Human Cytomegalovirus Immediate-Early mRNA Detection by Nucleic Acid Sequence-Based Amplification as a New Parameter for Preemptive Therapy in Bone Marrow Transplant Recipients [PDF]
, 2000 Giuseppe Gerna +8 more
openalex +1 more source
A Sensitivity Study for Interpreting Nucleic Acid Sequence Screening Regulatory and Guidance Documentation: Toward a Foundational Synthetic Nucleic Acid Sequence Screening Framework. [PDF]
Appl BiosafGemler BT +4 more
europepmc +1 more source
Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derived Nucleic Acid Sequence. [PDF]
Chembiochem, 2017 Nejad MI +4 more
europepmc +1 more source