Results 241 to 250 of about 376,743 (310)

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Advanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo, Grant Phillips, Sriganesh Srihari, Áine Farrell, Binny Jaradi, Kira J. Fitzpatrick, John W. Yaxley, Hemamali Samaratunga, Paul N. Mainwaring, Ke‐lin Ru, Darren J. Korbie, Scott A. Tomlins, Matthew J. Roberts, Robert A. Gardiner, Matt Trau   +14 more
wiley   +1 more source

Application of SNV Detection Methods for Market Control of Food Products from New Genomic Techniques. [PDF]

Int J Mol Sci
Bernacka KU, Michalski K, Wojciechowski M, Sowa S.   +3 more
europepmc   +1 more source

Split Aptameric Turn-On Fluorescence Sensor for Detection of Sequence Specific Nucleic Acid at Ambient Temperature

, 2018
Nanami Kikuchi
openalex   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Highly Sensitive Hybridization Chain Reaction-Based miRNA Detection Technology Using Diffusivity Analysis of Fluorescent Probe-Modified miRNA Particles. [PDF]

Sensors (Basel)
Nakai M, Watanabe Y, Koda M, Sakamoto C, Hasegawa T, Chuang HS, Sakamoto H.   +6 more
europepmc   +1 more source

An ERA-CRISPR/Cas12a Method for Highly Sensitive Detection of Human Adenovirus Type 55. [PDF]

Diagnostics (Basel)
Zhang L, Luo Z, Wang T, Han Y, Ye F, Wang C, Chen Y, Zhang J.   +7 more
europepmc   +1 more source

Efficient transgenic maize (Zea Mays L.) detection using low-depth next-generation sequencing. [PDF]

Sci Rep
Qi X, Zhao X, Lyu M, Wu K, Liu N, Li R, Xu C, Shen R, Zhou Z, Wang C, Zhang C, Wang YS, Lan Q, Wang Y.   +13 more
europepmc   +1 more source

Detection and molecular analysis of betacoronaviruses (family Coronaviridae) in hedgehogs (Erinaceus roumanicus) in Hungary. [PDF]

Arch Virol
Reuter G, Cora CE, Takáts K, Boros Á, Mátics R, Balázs B, Pankovics P.   +6 more
europepmc   +1 more source

Rewriting Tumor Entry Rules: Microfluidic Polyplexes and Tumor-Penetrating Strategies-A Literature Review. [PDF]

Pharmaceutics
Volovat SR, Augustin IG, Volovat C, Vasilache I, Ostafe M, Panaite DI, Burlacu A, Volovat CC.   +7 more
europepmc   +1 more source