Results 251 to 260 of about 698,636 (336)

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Molecular recognition and structural plasticity in amyloid-nucleic acid complexes. [PDF]

J Struct Biol
Kukreja R, Latham MP.
europepmc   +1 more source

Detection of Dengue Viral RNA Using a Nucleic Acid Sequence-Based Amplification Assay

, 2001
Shuenn-Jue Wu, Eun Mi Lee, Ravithat Putvatana, Roxanne N. Shurtliff, Kevin R. Porter, Suharyono Wuryadi, Douglas M. Watts, Chwan‐Chuen King, Gerald S. Murphy, Curtis G. Hayes, Joseph Romano   +10 more
openalex   +1 more source

DISSYMMETRY IN NUCLEOTIDE SEQUENCE OF DESOXYPENTOSE NUCLEIC ACIDS

Journal of Biological Chemistry, 1950
Erwin Chargaff, Stephen Zamenhof, George Brawerman   +2 more
openaire   +3 more sources

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

The secret life of RNA and lipids. [PDF]

RNA Biol
Czerniak T, Saenz JP.
europepmc   +1 more source

Nucleic Acid Sequence-Based Amplification of Aspergillus RNA in Blood Samples

, 2001
Juergen Loeffler, Holger Hebart, Philipp Cox, Nicole Flues, Ulrike Schumacher, Hermann Einsele   +5 more
openalex   +1 more source

An Antagonism Between Ethylene Signaling and DNA Methylation Orchestrates the Progression of Leaf Senescence in Non‐heading Chinese Cabbage

Advanced Science, EarlyView.
CMT2 mediates the maintenance of DNA methylation on the promoters of SAGs, thereby inhibiting EIN3A untimely activating SAGs’ expression. Aging‐impelled striking upregulation of EIN3A strongly suppresses the expression of CMT2 to reduce the methylation level, which releases the activation of EIN3A on SAGs, thus initiating and accelerating the ...
Dingyu Zhang, Yong Luo, Han Wang, Xiaofeng Li, Liming Miao, Lu Gao, Haibo Hao, Xinman Wang, Benke Kuai, Hongfang Zhu, Guodong Ren   +10 more
wiley   +1 more source

Cas12a Cis-cleavage mediated lateral flow assay enables multiplex and ultra-specific nucleic acid detection. [PDF]

Nat Commun
Lin M, Qiu Z, Hao M, Qi W, Zhang T, Shen Y, Xiao H, Liang C, Xie L, Jiang Y, Cheng M, Tian T, Zhou X.   +12 more
europepmc   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source