Results 261 to 270 of about 698,636 (336)

From Code to Life: The AI‐Driven Revolution in Genome Editing

Advanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li, Wasi Ullah Khan, Genxiang Bai, Chao Dong, Jungang Wang, Youpeng Zhang, Chong Wang, Hongbin Zhang, Wenyi Wang, Ming Luo, Fei Chen   +10 more
wiley   +1 more source

Advances in Research on Isothermal Signal Amplification Mediated MicroRNA Detection of Clinical Samples: Application to Disease Diagnosis. [PDF]

Biosensors (Basel)
Han Y, Sun X, Cai S.
europepmc   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

hAb-Convergent: an antibody rearrangement analysis system for therapeutic antibody engineering based on convergent evolution. [PDF]

Nucleic Acids Res
Wang J, Ge X, Sun Q, Chen M, Qin S, Liu D, Deng T, Ma J, Hu S, Jin R, Tong Z, Wu L.   +11 more
europepmc   +1 more source

A Nucleic Acid Sequence–Based Amplification Method To Detect Salmonella enterica Serotype Enteritidis Strain PT4 in Liquid Whole Egg

, 2002
Nigel Cook, J. A. Ellison, Anna Kurdziel, S. A. Simpkins, John P. Hays   +4 more
openalex   +1 more source

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source

Recent advances in CRISPR-based single-nucleotide fidelity diagnostics. [PDF]

Commun Med (Lond)
Kohabir KAV, Sistermans EA, Wolthuis RMF.   +2 more
europepmc   +1 more source

Role of Tunneling Nanotubes in Arachidonic Acid Transfer and Macrophage Function Reprogramming in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen, Shangyumeng Zhao, Xiaoli Xie, Jiaqi Wang, Miao Su, Lixian Zhang, Ruolin Cui, Dongqiang Zhao   +7 more
wiley   +1 more source

Belowground podcast: Digital droplet PCR to estimate root biomass and species profiling from soil samples. [PDF]

Plant Physiol
Khan M.
europepmc   +1 more source

Nucleic acid sequence-based amplification methods to detect avian influenza virus

, 2003
Lok Ting Lau, J. Banks, Rebecca Aherne, Ian H. Brown, Natalie Dillon, Richard A. Collins, Ka-Yun Chan, Yin‐Wan Wendy Fung, Jun Xing, Albert Cheung Hoi Yu   +9 more
openalex   +1 more source