Results 281 to 290 of about 1,249,290 (394)

Nucleic Acid Sequence-Based Amplification of Aspergillus RNA in Blood Samples

, 2001
Juergen Loeffler, Holger Hebart, Philipp Cox, Nicole Flues, Ulrike Schumacher, Hermann Einsele   +5 more
openalex   +1 more source

PVC Nanoplastics Exposure Exacerbates Asthma through R‐Loop Accumulation and Subsequent STING Activation in Macrophages

Advanced Science, EarlyView.
Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao, Yixing Huang, Mingcong Deng, Chunkai Zhang, Dan Zu, Hanyi He, Yangchan Hu, Yuke Zhong, Chen Liang, Haidong Liu, Wumin Dai, Yanhua He, Yaoshu Teng, Ji Jing, Yin Shi, Xiangdong Cheng, Zu Ye   +16 more
wiley   +1 more source

Detection of HIV-1 RNA by nucleic acid sequence-based amplification combined with fluorescence correlation spectroscopy.

Proceedings of the National Academy of Sciences of the United States of America, 1996
F. Oehlenschläger, P. Schwille, M. Eigen   +2 more
semanticscholar   +1 more source

A Comprehensive Lateral Flow Strip Assay for On‐Site mRNA Vaccine Quality Control in Decentralized Manufacturing

Advanced Science, EarlyView.
A rapid, portable lateral flow strip assay for on‐site mRNA quality control is developed, enabling sequence‐independent analysis of 5' capping, integrity, and LNPs encapsulation efficiency. This cost‐effective method offers real‐time stability monitoring, reduced sample requirements, and comparable accuracy to standard techniques, enhancing ...
Dengwang Luo, Ziwei Zhang, Jing Guo, Jieli Zhang, Arong Huang, Qinghao Cao, Jiangnan Zheng, Yingjin Yuan, Daming Wang, Yuhong Cao   +9 more
wiley   +1 more source

Design of a lateral flow assay targeting the conserved NIID_2019-nCoV_N gene region for molecular viral diagnosis. [PDF]

Braz J Med Biol Res
Derin DÇ, Gültekin E.
europepmc   +1 more source

APPLICATION OF NUCLEIC ACID SEQUENCE-BASED AMPLIFICATION FOR THE DETECTION OF VIABLE FOODBORNE PATHOGENS: PROGRESS AND CHALLENGES

, 2006
D. Rodríguez-Lázaro, M. Hernández, M. D’Agostino, N. Cook   +3 more
semanticscholar   +1 more source

Comparison and Evaluation of Real-Time PCR, Real-Time Nucleic Acid Sequence-Based Amplification, Conventional PCR, and Serology for Diagnosis of Mycoplasma pneumoniae

Journal of Clinical Microbiology, 2003
K. Templeton, S. A. Scheltinga, A. Graffelman, Jolanda M Van Schie, Jantine W Crielaard, P. Sillekens, P. J. van den Broek, H. Goossens, M. Beersma, E. Claas   +9 more
semanticscholar   +1 more source

Polyhalogenated Carbazole Impairs Dopaminergic Neurons through Dysregulation of Liquid–Liquid Phase Separation in Caenorhabditis elegans

Advanced Science, EarlyView.
Polyhalogenated carbazoles (PHCZ), persistent environmental contaminants, preferentially accumulate in neuronal tissues. Studies using Caenorhabditis elegans and human neuronal cell lines reveal that PHCZ induce dopaminergic neurodegeneration by promoting liquid–liquid phase separation of α‐synuclein, reducing condensate fluidity, impairing ...
Yuhang Luo, Hongbo Xu, Pei Peng, Xinhe Lu, Qian Zhou, Ziqing Gao, Cheng Tang, Hongyan Yin, Ying Cai, Gaga Mahai, Zhiqiang Zhu, Zuojun Liu, Hanzeng Li, Shunqing Xu   +13 more
wiley   +1 more source

Tailoring Cas12a functionality with a user-friendly and versatile crRNA variant toolbox. [PDF]

Nat Commun
Han J, Min Y, Hu L, Chen JJ, Zhang SX, Li XF, Cheng ZH, Liu DF, Yu HQ.   +8 more
europepmc   +1 more source

Ultrasound‐Mediated Biotransfection of Engineered Bone Marrow Mesenchymal Stem Cells in Treated Bone Defects through Intracellular Cavitation

Advanced Science, EarlyView.
Ultrasound‐mediated biotransfection through intracellular cavitation increases plasmid nuclear translocation and gene transfection efficiency by 284.7% and 131.6% in engineered bone marrow mesenchymal stem cells (BMSCs) compared to traditional ultrasound‐targeted microbubble destruction techniques. The maintained bone morphogenetic protein 2 expression
Zhili Xu, Huijuan Xin, Yu Wang, Renhao Xu, Yanni He, Meijun Zhou, Zhengqiang Yuan, Hongmei Liu   +7 more
wiley   +1 more source