Results 21 to 30 of about 1,295,417 (401)
Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA
Protein–RNA and protein–DNA complexes play critical roles in biology. Despite considerable recent advances in protein structure prediction, the prediction of the structures of protein–nucleic acid complexes without homology to known complexes is a ...
M. Baek+5 more
semanticscholar +1 more source
Monitoring of Chlamydia trachomatis infections after antibiotic treatment using RNA detection by nucleic acid sequence based amplification. [PDF]
S. Morré+9 more
semanticscholar +2 more sources
Enteroviruses are ubiquitous mammalian pathogens that can produce mild to life-threatening disease. We developed a multimodal, rapid, accurate and economical point-of-care biosensor that can detect nucleic acid sequences conserved amongst 96% of all ...
Veeren M. Chauhan+5 more
doaj +1 more source
NASCUP: Nucleic Acid Sequence Classification by Universal Probability
Nucleic acid sequence classification is a fundamental task in the field of bioinformatics. Due to the increasing amount of unlabeled nucleotide sequences, fast and accurate classification of them on a large scale has become crucial.
Sunyoung Kwon+5 more
doaj +1 more source
Argonaute protein-based nucleic acid detection technology
It is vital to diagnose pathogens quickly and effectively in the research and treatment of disease. Argonaute (Ago) proteins are recently discovered nucleases with nucleic acid shearing activity that exhibit specific recognition properties beyond CRISPR ...
Zhiyun Wu+3 more
doaj +1 more source
Analysis of Nucleotide Sequences Similarity and Protein Prediction of Some Resistance Genes in Escherichia coli Isolated from Iraqi Patients with Urinary Tract Infections [PDF]
Antibiotic resistance leads to a dramatic increase in the morbidity and mortality caused by infectious diseases. Even though estimates vary widely, the economic cost of antimicrobial-resistant bacteria is on a rise.
R Kadhim Mohammed, A Attallah Ibrahim
doaj +1 more source
Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
In nature, genomes have been optimized by the evolution of their nucleic acid sequences. The design of peptide-like carriers as synthetic sequences provides a strategy for optimizing multifunctional targeted nucleic acid delivery in an iterative process.
Yanfang Wang, Ernst Wagner
doaj +1 more source
Ab Initio Nucleic Acid Folding Simulations Using a Physics-Based Atomistic Free Energy Model [PDF]
Performing full-resolution atomistic simulations of nucleic acid folding has remained a challenge for biomolecular modeling. Understanding how nucleic acids fold and how they transition between different folded structures as they unfold and refold has important implications for biology.
arxiv +1 more source
The interaction between proteins and nucleic acid plays an important role in many processes, such as transcription, translation and DNA repair. The mechanisms of related biological events can be understood by exploring the function of proteins in these ...
Lei Xu, Shanshan Jiang, Q. Zou
semanticscholar +1 more source
Nucleic Acid Vaccines against SARS-CoV-2
The coronavirus disease 2019 (COVID-19) has spread worldwide and imposed a substantial burden on human health, the environment, and socioeconomic development, which has also accelerated the process of nucleic acid vaccine development and licensure ...
Ying Liu, Qing Ye
doaj +1 more source