Results 21 to 30 of about 376,743 (310)
Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
Pharmaceutics, 2020 In nature, genomes have been optimized by the evolution of their nucleic acid sequences. The design of peptide-like carriers as synthetic sequences provides a strategy for optimizing multifunctional targeted nucleic acid delivery in an iterative process.
Yanfang Wang, Ernst Wagner
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Analysis of Nucleotide Sequences Similarity and Protein Prediction of Some Resistance Genes in Escherichia coli Isolated from Iraqi Patients with Urinary Tract Infections [PDF]
Archives of Razi Institute, 2022 Antibiotic resistance leads to a dramatic increase in the morbidity and mortality caused by infectious diseases. Even though estimates vary widely, the economic cost of antimicrobial-resistant bacteria is on a rise.
R Kadhim Mohammed, A Attallah Ibrahim
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Sequence Multiplicity within Spherical Nucleic Acids [PDF]
ACS Nano, 2020 The synthesis and evaluation of spherical nucleic acids (SNAs) incorporating two physically and chemically distinct classes of oligonucleotides (ODNs) at programmed ratios are described. These SNAs are single entity agents that enter the same target cell at defined stoichiometries, and as such allow one to control important cell signaling and ...
Ziyin N. Huang +4 more
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Multiple sequence alignments of partially coding nucleic acid sequences
BMC Bioinformatics, 2005 Background High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data.
Fried Claudia +3 more
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Aggregate, 2023 The ongoing outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) pandemic has posed significant challenges in early viral diagnosis. Hence, it is urgently desirable to develop a rapid, inexpensive, and sensitive method to aid point‐of‐
Qin Zhang +10 more
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Nucleic Acid Vaccines against SARS-CoV-2
Vaccines, 2022 The coronavirus disease 2019 (COVID-19) has spread worldwide and imposed a substantial burden on human health, the environment, and socioeconomic development, which has also accelerated the process of nucleic acid vaccine development and licensure ...
Ying Liu, Qing Ye
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Heliyon, 2023 The clustered regularly interspaced short palindromic DNA sequence repeats (CRISPR) and CRISPR-associated (Cas) (CRISPR/Cas) systems are currently applied not only as a gene editing tool but also as a novel molecular diagnostic technique.
Jian Zhou +4 more
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Nanomaterials, 2019 Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms.
Paul Zakrevsky +5 more
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Identification of nucleic acid binding sites on translin-associated factor X (TRAX) protein. [PDF]
PLoS ONE, 2012 Translin and TRAX proteins play roles in very important cellular processes such as DNA recombination, spatial and temporal expression of mRNA, and in siRNA processing.
Gagan Deep Gupta, Vinay Kumar
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iTriplet, a rule-based nucleic acid sequence motif finder
Algorithms for Molecular Biology, 2009 Background With the advent of high throughput sequencing techniques, large amounts of sequencing data are readily available for analysis. Natural biological signals are intrinsically highly variable making their complete identification a computationally ...
Gunderson Samuel I +2 more
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