Results 21 to 30 of about 709,713 (351)
Mechanisms of HIV-1 Nucleocapsid Protein Inhibition by Lysyl-Peptidyl-Anthraquinone Conjugates [PDF]
, 2016 The Nucleocapsid protein NCp7 (NC) is a nucleic acid chaperone responsible for essential steps of the HIV-1 life cycle and an attractive candidate for drug development.
Alice Sosic +12 more
core +2 more sources
Identification of nucleic acid binding sites on translin-associated factor X (TRAX) protein. [PDF]
PLoS ONE, 2012 Translin and TRAX proteins play roles in very important cellular processes such as DNA recombination, spatial and temporal expression of mRNA, and in siRNA processing.
Gagan Deep Gupta, Vinay Kumar
doaj +1 more source
The Jena Library of Biological Macromolecules - JenaLib [PDF]
, 2009 The JenaLib database ("www.fli-leibniz.de/IMAGE.html":http://www.fli-leibniz.de/IMAGE.html) offers value-added information for all Protein Data Bank (PDB) and Nucleic Acid Database (NDB) entries.
Juergen Suehnel, Rolf Huehne
core +2 more sources
Nanomaterials, 2019 Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms.
Paul Zakrevsky +5 more
doaj +1 more source
A CRISPR-based nucleic acid detection method for severe fever with thrombocytopenia syndrome virus
Virus Research, 2022 Objective: Fever with thrombocytopenia syndrome virus (SFTS) is a tick-borne infection now known to spread among humans as an aerosol, which has resulted in several outbreaks across Asia over the past decade.
Yansong Zhang +15 more
doaj +1 more source
tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA [PDF]
, 2009 A real-time nucleic acid sequence-based amplification assay, targeting tmRNA, was designed for the rapid identification of Staphylococcus aureus. The selectivity of the assay was confirmed against a panel of 76 Staphylococcus strains and species and 22 ...
Anonymous +9 more
core +1 more source
iTriplet, a rule-based nucleic acid sequence motif finder
Algorithms for Molecular Biology, 2009 Background With the advent of high throughput sequencing techniques, large amounts of sequencing data are readily available for analysis. Natural biological signals are intrinsically highly variable making their complete identification a computationally ...
Gunderson Samuel I +2 more
doaj +1 more source
Insights into DNA platination within unusual structural settings [PDF]
, 2011 2D [1H, 15N] HSQC NMR spectroscopy has been used to monitor reaction and product formation between [Pt(15NH3)2I2] and nucleic acids possessing irregular topologies and containing site specific phosphorothioate substitution in the phosphodiester backbone.
Harvie, Stephanie +2 more
core +2 more sources
Applied Microscopy, 2019 Fluorescence imaging of nucleic acids is a very important technique necessary to understand gene expression and the resulting changes in cell function. This mini-review focuses on sequence-specific fluorescence imaging of intracellular RNA and methylated
Akimitsu Okamoto
doaj +1 more source
Improving the specificity of nucleic acid detection with endonuclease-actuated degradation
Communications Biology, 2022 A new method, SENTINEL, improves the specificity of nucleic acid target sequence identification via a combination of isothermal amplification and sequence-specific DNA endonucleases. The method can discriminate single base-pair differences and takes less
Roger S. Zou +11 more
doaj +1 more source