Results 21 to 30 of about 1,249,290 (394)

Monitoring of Chlamydia trachomatis infections after antibiotic treatment using RNA detection by nucleic acid sequence based amplification [PDF]

Molecular Pathology, 1998
Servaas A. Morré, Peter Sillekens, Marc Jacobs, S. de Blok, J M Ossewaarde, P. van Aarle, Bob van Gemen, Jan M.M. Walboomers, Chris J.L.M. Meijer, A J van den Brule   +9 more
openalex   +2 more sources

Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]

, 2011
Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Troiber, Christina, Wagner, Ernst
core   +1 more source

An in silico approach to identification, categorization and prediction of nucleic acid binding proteins

bioRxiv, 2020
The interaction between proteins and nucleic acid plays an important role in many processes, such as transcription, translation and DNA repair. The mechanisms of related biological events can be understood by exploring the function of proteins in these ...
Lei Xu, Shanshan Jiang, Q. Zou
semanticscholar   +1 more source

An AIEgen/graphene oxide nanocomposite (AIEgen@GO)‐based two‐stage “turn‐on” nucleic acid biosensor for rapid detection of SARS‐CoV‐2 viral sequence

Aggregate, 2023
The ongoing outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) pandemic has posed significant challenges in early viral diagnosis. Hence, it is urgently desirable to develop a rapid, inexpensive, and sensitive method to aid point‐of‐
Qin Zhang, Bohan Yin, Jianhua Hao, Linjie Ma, Yingying Huang, Xueying Shao, Chuanqi Li, Zhiqin Chu, Changqing Yi, Siu Hong Dexter Wong, Mo Yang   +10 more
doaj   +1 more source

Nucleic Acid Vaccines against SARS-CoV-2

Vaccines, 2022
The coronavirus disease 2019 (COVID-19) has spread worldwide and imposed a substantial burden on human health, the environment, and socioeconomic development, which has also accelerated the process of nucleic acid vaccine development and licensure ...
Ying Liu, Qing Ye
doaj   +1 more source

Impact of Nucleic Acid Sequencing on Viroid Biology [PDF]

International Journal of Molecular Sciences, 2020
The early 1970s marked two breakthroughs in the field of biology: (i) The development of nucleotide sequencing technology; and, (ii) the discovery of the viroids. The first DNA sequences were obtained by two-dimensional chromatography which was later replaced by sequencing using electrophoresis technique.
Charith Raj Adkar-Purushothama, Jean-Pierre Perreault   +1 more
openaire   +4 more sources

Recent advances and challenges of the use of the CRISPR/Cas system as a non-nucleic acid molecular diagnostic

Heliyon, 2023
The clustered regularly interspaced short palindromic DNA sequence repeats (CRISPR) and CRISPR-associated (Cas) (CRISPR/Cas) systems are currently applied not only as a gene editing tool but also as a novel molecular diagnostic technique.
Jian Zhou, Xue-mei Ren, Xin Wang, Zhuo Li, Cory J Xian   +4 more
doaj   +1 more source

Mechanisms of HIV-1 Nucleocapsid Protein Inhibition by Lysyl-Peptidyl-Anthraquinone Conjugates [PDF]

, 2016
The Nucleocapsid protein NCp7 (NC) is a nucleic acid chaperone responsible for essential steps of the HIV-1 life cycle and an attractive candidate for drug development.
Alice Sosic, Barbara Gatto, Cristina Parolin, Dan Fabris, Giuseppe Zagotto, Giuseppina Sabatino, Guo J., Ilaria Carli, Laura Sinigaglia, Marta Cappellini, Morellet N., Paolo Rovero, You J. C.   +12 more
core   +2 more sources

Identification of nucleic acid binding sites on translin-associated factor X (TRAX) protein. [PDF]

PLoS ONE, 2012
Translin and TRAX proteins play roles in very important cellular processes such as DNA recombination, spatial and temporal expression of mRNA, and in siRNA processing.
Gagan Deep Gupta, Vinay Kumar
doaj   +1 more source

The Jena Library of Biological Macromolecules - JenaLib [PDF]

, 2009
The JenaLib database ("www.fli-leibniz.de/IMAGE.html":http://www.fli-leibniz.de/IMAGE.html) offers value-added information for all Protein Data Bank (PDB) and Nucleic Acid Database (NDB) entries.
Juergen Suehnel, Rolf Huehne
core   +2 more sources