Results 291 to 300 of about 698,636 (336)

Iron Oxide Nanoparticles Modified with Galloylated DNA for Magnetically Enhanced DNA‐Directed Assembly

Advanced Science, EarlyView.
A simple one‐step method is presented for DNA functionalization of iron oxide nanoparticles (IONP) using multidentate galloylated DNA. The DNA‐modified IONPs exhibit unique DNA binding properties of magnetically enhanced DNA interconnects. This study underscores the importance of nanoparticle (NP) effects in DNA sequence design and highlights the ...
Murali Golla, Hyunjin Jeon, Shine K. Albert, Hojun Lee, Seulki Kang, Moon Jeong Park, So‐Jung Park   +6 more
wiley   +1 more source

High-Fidelity, One-Pot Nucleic Acid Amplification via OMEGA IsrB Nickase Cycling for Clinical Pathogen Detection. [PDF]

JACS Au
Liao Y, Sun Y, Yu H, Ren J, He F.
europepmc   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Nucleic Acid-Modified Nanoparticles for Cancer Therapeutic Applications. [PDF]

Small
Qin Y, Chen X, Willner I.
europepmc   +1 more source

Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome

Advanced Science, EarlyView.
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang, Xiangbing Wu, Wenming Li, Haifeng Zhang, Yijun Wang, Jing Xu, Wenhao Li, Yi Qin, Zebin Wu, Gaoran Ge, Shujun Lv, Lu Mao, Liangliang Wang, Dechun Geng   +13 more
wiley   +1 more source

A Convenient Fluorogenic Detection Strategy for Phosphorothioate Modification of DNA Through Photocatalytic Oligonucleotide-Templated Reaction. [PDF]

Biomolecules
Jing N, Qin Y, Fan X, Wang Q, Wang J, You F, Tang X.   +6 more
europepmc   +1 more source

PAM-free hairpin target binding activates trans-cleavage activity of Cas12a. [PDF]

Nucleic Acids Res
Li X, Zhu Z, Wu J, Li C, Liu Z, Wang J, Li P, Zhang Z, Huang Y, Hong J, Wu T.   +10 more
europepmc   +1 more source

Introducing the PARCH Scale for Quantifying the Hydropathy of Nucleic Acids and Nucleic Acid-Protein Complexes. [PDF]

Langmuir
Mandal R, Ji J, Sheridan CN, Baur AM, Noel AC, Nangia S.   +5 more
europepmc   +1 more source

SHARK: web server for alignment-free homology assessment for intrinsically disordered and unalignable protein regions. [PDF]

Nucleic Acids Res
Willis Chow CF, Scheremetjew M, Moon H, Ghosh S, Hadarovich A, Hersemann L, Toth-Petroczy A.   +6 more
europepmc   +1 more source

Random guide-independent DNA cleavage from the Argonaute of Exiguobacterium sp. AB2. [PDF]

BMC Microbiol
Cañiza MAM, Dy RLV.
europepmc   +1 more source