Results 301 to 310 of about 836,134 (332)

Rational recognition of nucleic acid sequences

Current Opinion in Biotechnology, 1999
Recent progress in synthetic and computational chemistry has made it possible to develop certain novel drug candidates. Drug candidates for genetic diseases, such as cancer, may also be designed on the basis of structural information obtained using X-ray analysis and NMR, as well as evidence from biological techniques applied to natural products - DNA (
J. William Lown, Hirokazu Iida, Guofeng Jia   +2 more
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On-chip real-time nucleic acid sequence-based amplification for RNA detection and amplification

, 2011
Development of integrated systems for nucleic acid analyses is mainly driven by the requirement for fast and simple clinical and environmental diagnostics.
M. Tsaloglou, M. Bahi, E. Waugh, H. Morgan, M. Mowlem   +4 more
semanticscholar   +1 more source

Introduction to Nucleic Acid Sequencing

2019
Determining the order of nucleotide in the biological macromolecules has laid the foundation for understanding the biology of an organism. Over the last 50 years, genomics has been revolutionized with the researchers producing newer techniques and technologies leading to innovations in the field of DNA sequencing.
Francis Amirtharaj, Preetha J. Shetty, Noor Ahmad Shaik   +2 more
openaire   +2 more sources

The GenBank nucleic acid sequence database

Comput. Appl. Biosci., 1985
The GenBank nucleic acid sequence database is a computer-based collection of all published DNA and RNA sequences; it contains over five million bases in close to six thousand sequence entries drawn from four thousand five hundred published articles. Each
C. Burks, J. Fickett, Walter B. Goad, M. Kanehisa, F. Lewitter, W. Rindone, C. Swindell, Chang-Shung Tung, H. Bilofsky   +8 more
semanticscholar   +1 more source

Nucleic Acid Sequence Bank

Science, 1980
In the report by T. Kakunaga and J. D. Crow (25 July, p. 505), Fig. 1 on page 506 should have been printed as follows: [See figure in the PDF file]
Bruce C. Orcutt, M. O. Dayhoff, Robert M. Schwartz, H.R. Chen, Lois T. Hunt, Winona C. Barker   +5 more
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Protein and Nucleic Acid Sequence Database Systems.

Annual Review of Biophysics and Bioengineering, 1983
Of all of the information in the life sciences, the chemical structures of the nucleic acids and proteins are among the most fundamental. Their importance is reflected by the large number of research workers currently involved in sequencing studies and ...
B. C. Orcutt, D. G. George, M. O. Dayhoff   +2 more
semanticscholar   +1 more source

Doublet frequencies in sequenced nucleic acids

Journal of Molecular Evolution, 1975
A doublet frequency count (set of frequencies of the 16 possible two-base sequences) can be calculated from the experimentally determined overall sequence of a nucleic acid. In this paper, a statistical methodology is developed for comparing such counts with random, with others of the same type or with doublet proportions found in whole DNAs.
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Nucleic Acid Sequence Determination

1980
It is often emphasised how closely the structure and function of biological materials are related to each other. This is certainly true for all biological macromolecules, but to some extent it is also true for any chemical substance: whether it takes part in a simple chemical reaction or in a complex biological process, the function of the molecule is ...
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Sequences in Genetic Nucleic Acids

1973
The basic chemical material of the gene is DNA and all the information for the developing organism is contained in the form of a specific nucleotide sequence in this DNA. In order to understand the gene more fully and the way in which the information is encoded it is necessary to study these nucleotide sequences.
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Nucleic acid sequence analysis software for microcomputers

Analytical Biochemistry, 1990
It is clear that a computer-aided data control system is required for even small laboratories generating nucleic acid data. While the molecular biologist at many universities and large research institutions has access to mainframe computers and nucleic acid sequence analysis software, many find it more convenient to perform sequence analysis on ...
openaire   +2 more sources