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Nucleic acid and protein sequence databases

Bioinformatics, 1985
Nucleic acid and protein sequences contain a wealth of information of interest to molecular biologists. The advent of molecular sequence databases provides a unique opportunity for the computer analysis of all available sequences. Sequence databases serve two main functions: (i) to facilitate comparisons with newly determined sequences, and (ii) to act
M.J. Bishop, G.G. Kneale
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Introduction to Nucleic Acid Sequencing

2019
Determining the order of nucleotide in the biological macromolecules has laid the foundation for understanding the biology of an organism. Over the last 50 years, genomics has been revolutionized with the researchers producing newer techniques and technologies leading to innovations in the field of DNA sequencing.
Francis Amirtharaj   +2 more
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The GenBank nucleic acid sequence database

Comput. Appl. Biosci., 1985
The GenBank nucleic acid sequence database is a computer-based collection of all published DNA and RNA sequences; it contains over five million bases in close to six thousand sequence entries drawn from four thousand five hundred published articles. Each
C. Burks   +8 more
semanticscholar   +1 more source

System analysis and nucleic acid sequence banks

Biochimie, 1985
The mass of published nucleic acid sequence data has required the design of several computerized data bases. We show that this activity is related to the methodology of System Analysis and that data bases are a means of modeling biological knowledge. As an example, the ACNUC data base we have created is presented.
Gouy, Manolo   +2 more
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Protein and Nucleic Acid Sequence Database Systems.

Annual Review of Biophysics and Bioengineering, 1983
Of all of the information in the life sciences, the chemical structures of the nucleic acids and proteins are among the most fundamental. Their importance is reflected by the large number of research workers currently involved in sequencing studies and ...
B. C. Orcutt   +2 more
semanticscholar   +1 more source

Doublet frequencies in sequenced nucleic acids

Journal of Molecular Evolution, 1975
A doublet frequency count (set of frequencies of the 16 possible two-base sequences) can be calculated from the experimentally determined overall sequence of a nucleic acid. In this paper, a statistical methodology is developed for comparing such counts with random, with others of the same type or with doublet proportions found in whole DNAs.
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Nucleic Acid Sequence Bank

Science, 1980
In the report by T. Kakunaga and J. D. Crow (25 July, p. 505), Fig. 1 on page 506 should have been printed as follows: [See figure in the PDF file]
Bruce C. Orcutt   +5 more
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Nucleic Acid Sequence Determination

1980
It is often emphasised how closely the structure and function of biological materials are related to each other. This is certainly true for all biological macromolecules, but to some extent it is also true for any chemical substance: whether it takes part in a simple chemical reaction or in a complex biological process, the function of the molecule is ...
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Nucleic acid sequences handbook

1981
International ...
Gautier, Christian   +3 more
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Sequences in Genetic Nucleic Acids

1973
The basic chemical material of the gene is DNA and all the information for the developing organism is contained in the form of a specific nucleotide sequence in this DNA. In order to understand the gene more fully and the way in which the information is encoded it is necessary to study these nucleotide sequences.
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