Results 31 to 40 of about 694,635 (336)
iTriplet, a rule-based nucleic acid sequence motif finder
Algorithms for Molecular Biology, 2009 Background With the advent of high throughput sequencing techniques, large amounts of sequencing data are readily available for analysis. Natural biological signals are intrinsically highly variable making their complete identification a computationally ...
Gunderson Samuel I +2 more
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The polymerase chain reaction [PDF]
, 2003 The Polymerase Chain Reaction (PCR) is a technique for the in vitro synthesis of billions of copies of a specific nucleic acid sequence by performing successive rounds of in vitro nucleic acid replication.
Paulton, M P, Thomas, P C
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ENA as an Information Hub [PDF]
, 2010 The European Nucleotide Archive (ENA; "http://www.ebi.ac.uk/ena/":http://www.ebi.ac.uk/ena/) is a comprehensive repository for public nucleotide sequence data from nearly four hundred thousand taxonomic nodes.
Bob Vaughan +5 more
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Nanomaterials, 2019 Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms.
Paul Zakrevsky +5 more
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The Jena Library of Biological Macromolecules - JenaLib [PDF]
, 2009 The JenaLib database ("www.fli-leibniz.de/IMAGE.html":http://www.fli-leibniz.de/IMAGE.html) offers value-added information for all Protein Data Bank (PDB) and Nucleic Acid Database (NDB) entries.
Juergen Suehnel, Rolf Huehne
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Furan-PNA : a mildly inducible irreversible interstrand crosslinking system targeting single and double stranded DNA [PDF]
, 2016 We here report on the design and synthesis of tailor-made furan-modified peptide nucleic acid (PNA) probes for covalent targeting of single stranded DNA through a crosslinking strategy.
Corradini, Roberto +3 more
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tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA [PDF]
, 2009 A real-time nucleic acid sequence-based amplification assay, targeting tmRNA, was designed for the rapid identification of Staphylococcus aureus. The selectivity of the assay was confirmed against a panel of 76 Staphylococcus strains and species and 22 ...
Anonymous +9 more
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DNA Ligase-Mediated Translation of DNA Into Densely Functionalized Nucleic Acid Polymers [PDF]
, 2013 We developed a method to translate DNA sequences into densely functionalized nucleic acids by using T4 DNA ligase to mediate the DNA-templated polymerization of 5′-phosphorylated trinucleotides containing a wide variety of appended functional groups ...
Hili, Ryan, Liu, David Ruchien, Niu, Jia
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Graph theoretic methods for the analysis of structural relationships in biological macromolecules [PDF]
, 2005 Subgraph isomorphism and maximum common subgraph isomorphism algorithms from graph theory provide an effective and an efficient way of identifying structural relationships between biological macromolecules.
Altschul +72 more
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Slow nucleic acid unzipping kinetics from sequence-defined barriers
, 2002 Recent experiments on unzipping of RNA helix-loop structures by force have shown that about 40-base molecules can undergo kinetic transitions between two well-defined `open' and `closed' states, on a timescale = 1 sec [Liphardt et al., Science 297, 733 ...
Cocco, S., Marko, J. F., Monasson, R.
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