Results 41 to 50 of about 709,713 (351)

Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases

open access: yesFrontiers in Genetics, 2014
The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3 ...
Kozo eTomita, Seisueke eYamashita
doaj   +1 more source

Logic devices based on nucleic acid self‐assembly

open access: yesInfoMat, 2021
Nucleic acids are natural macromolecules with the ability to store and transmit information based on the strict base‐pairing principle. Beyond the natural nucleic acid double helixes, various DNA/RNA nanostructures with customized geometries and ...
Xuehui Xu   +4 more
doaj   +1 more source

Mth10b, a unique member of the Sac10b family, does not bind nucleic acid. [PDF]

open access: yesPLoS ONE, 2011
The Sac10b protein family is regarded as a group of nucleic acid-binding proteins that are highly conserved and widely distributed within archaea. All reported members of this family are basic proteins that exist as homodimers in solution and bind to DNA
Yan-Feng Liu   +5 more
doaj   +1 more source

A method to find palindromes in nucleic acid sequences [PDF]

open access: yesBioinformation, 2013
Various types of sequences in the human genome are known to play important roles in different aspects of genomic functioning. Among these sequences, palindromic nucleic acid sequences are one such type that have been studied in detail and found to influence a wide variety of genomic characteristics.
Mani Shankar   +3 more
openaire   +2 more sources

Mechanistic studies on DNA damage by minor groove binding copper–phenanthroline conjugates [PDF]

open access: yes, 2005
Copper–phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline conjugates are used as research tools for studying nucleic acid structure and binding interactions.
Bales, Brian C.   +5 more
core   +2 more sources

Useful Microsoft® WordTM Macros for Molecular Biologists and Protein Chemists

open access: yesBioTechniques, 2000
Biologists today make extensive use of word processing programs for the production of research reports, literature reviews and grant proposals. Frequently, such programs become the default platform for viewing and the later publication of protein and ...
Gerry Shaw
doaj   +1 more source

Sensing of nucleic acid sequences using unmodifiednucleic acid as a probe [PDF]

open access: yesNucleic Acids Symposium Series, 2007
We present a strategy to generate a light-up fluorophore-aptamer pair. The strategy was based on a modification of a conventional DNA-staining dye to suppress its affinity to the original targets, and subsequent re-selection of aptamers that would bind to the modified dye.
Atsushi Narita   +2 more
openaire   +3 more sources

Secondary structure formation of homopolymeric single-stranded nucleic acids including force and loop entropy: implications for DNA hybridization

open access: yes, 2011
Loops are essential secondary structure elements in folded DNA and RNA molecules and proliferate close to the melting transition. Using a theory for nucleic acid secondary structures that accounts for the logarithmic entropy c ln m for a loop of length m,
Einert, Thomas R.   +2 more
core   +1 more source

Enhancing the selective extracellular location of a recombinant E. coli domain antibody by management of fermentation conditions [PDF]

open access: yes, 2015
The preparation of a recombinant protein using Escherichia coli often involves a challenging primary recovery sequence. This is due to the inability to secrete the protein to the extracellular space without a significant degree of cell lysis.
Finka, G   +3 more
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

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