Results 51 to 60 of about 1,249,290 (394)

Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases

Frontiers in Genetics, 2014
The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3 ...
Kozo eTomita, Seisueke eYamashita
doaj   +1 more source

CRISPR-induced DNA reorganization for multiplexed nucleic acid detection

Nature Communications, 2023
Nucleic acid sensing involving CRISPR technologies is powerful but has certain limitations, such as PAM sequence requirements and limited multiplexing.
Margot Karlikow, Evan Amalfitano, Xiaolong Yang, Jennifer Doucet, Abigail Chapman, Peivand Sadat Mousavi, Paige Homme, Polina Sutyrina, Winston Chan, Sofia Lemak, Alexander F. Yakunin, Adam G. Dolezal, Shana Kelley, Leonard J. Foster, Brock A. Harpur, Keith Pardee   +15 more
doaj   +1 more source

Mth10b, a unique member of the Sac10b family, does not bind nucleic acid. [PDF]

PLoS ONE, 2011
The Sac10b protein family is regarded as a group of nucleic acid-binding proteins that are highly conserved and widely distributed within archaea. All reported members of this family are basic proteins that exist as homodimers in solution and bind to DNA
Yan-Feng Liu, Nan Zhang, Hong-Wei Yao, Hong-Wei Yao, Xian-Ming Pan, Meng Ge   +5 more
doaj   +1 more source

Secondary structure formation of homopolymeric single-stranded nucleic acids including force and loop entropy: implications for DNA hybridization

, 2011
Loops are essential secondary structure elements in folded DNA and RNA molecules and proliferate close to the melting transition. Using a theory for nucleic acid secondary structures that accounts for the logarithmic entropy c ln m for a loop of length m,
Einert, Thomas R., Netz, Roland R., Orland, Henri   +2 more
core   +1 more source

Mechanistic studies on DNA damage by minor groove binding copper–phenanthroline conjugates [PDF]

, 2005
Copper–phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline conjugates are used as research tools for studying nucleic acid structure and binding interactions.
Bales, Brian C., Greenberg, Marc M., Kodama, Tetsuya, Meunier, Bernard, Pitié, Marguerite, Weledji, Yvonne N.   +5 more
core   +2 more sources

A method to find palindromes in nucleic acid sequences [PDF]

Bioinformation, 2013
Various types of sequences in the human genome are known to play important roles in different aspects of genomic functioning. Among these sequences, palindromic nucleic acid sequences are one such type that have been studied in detail and found to influence a wide variety of genomic characteristics.
Mani Shankar, Kanagaraj Sekar, Ramnath Anjana, Marthandan Kirti Vaishnavi   +3 more
openaire   +2 more sources

Useful Microsoft® WordTM Macros for Molecular Biologists and Protein Chemists

BioTechniques, 2000
Biologists today make extensive use of word processing programs for the production of research reports, literature reviews and grant proposals. Frequently, such programs become the default platform for viewing and the later publication of protein and ...
Gerry Shaw
doaj   +1 more source

Logic devices based on nucleic acid self‐assembly

InfoMat, 2021
Nucleic acids are natural macromolecules with the ability to store and transmit information based on the strict base‐pairing principle. Beyond the natural nucleic acid double helixes, various DNA/RNA nanostructures with customized geometries and ...
Xuehui Xu, Yingxu Shang, Fengsong Liu, Qiao Jiang, Baoquan Ding   +4 more
doaj   +1 more source

Enzyme-Free Translation of DNA into Sequence-Defined Synthetic Polymers Structurally Unrelated to Nucleic Acids [PDF]

, 2015
The translation of DNA sequences into corresponding biopolymers enables the production, function, and evolution of the macromolecules of life. In contrast, methods to generate sequence-defined synthetic polymers with similar levels of control have ...
Hili, Ryan, Liu, David R., Niu, Jia
core   +1 more source

Sensing of nucleic acid sequences using unmodifiednucleic acid as a probe [PDF]

Nucleic Acids Symposium Series, 2007
We present a strategy to generate a light-up fluorophore-aptamer pair. The strategy was based on a modification of a conventional DNA-staining dye to suppress its affinity to the original targets, and subsequent re-selection of aptamers that would bind to the modified dye.
Atsushi Narita, Yasuhiro Aoyama, Shinsuke Sando   +2 more
openaire   +3 more sources