Results 51 to 60 of about 1,295,417 (401)
Nucleic Acid Probes for Single-Molecule Localization Imaging of Cellular Biomolecules
Endogenous biomolecules in cells are the basis of all life activities. Directly visualizing the structural characteristics and dynamic behaviors of cellular biomolecules is significant for understanding the molecular mechanisms in various biological ...
Junyuan Wei+5 more
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The size of sequence databases, the rapid rate of generating sequence data and the need to routinely construct recombinant DNA molecules in molecular biological research necessitate the frequent handling and analysis of nucleotide and protein sequences ...
Hugh G. Patterton, Steven Graves
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Aptamers as Modular Components of Therapeutic Nucleic Acid Nanotechnology.
Nucleic acids play a central role in all domains of life, either as genetic blueprints or as regulators of various biochemical pathways. The chemical makeup of ribonucleic (RNA) or deoxyribonucleic (DNA) acids, generally represented by a sequence of four
Martin Panigaj+7 more
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Digital PCR has been promoted as a technique for obtaining absolute measures of the amount of nucleic acid target sequence in a sample, but still lacks standardization in data reporting.
Sherry J Coulter
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CRISPR-induced DNA reorganization for multiplexed nucleic acid detection
Nucleic acid sensing involving CRISPR technologies is powerful but has certain limitations, such as PAM sequence requirements and limited multiplexing.
Margot Karlikow+15 more
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tmRNA - a novel high-copy-number RNA diagnostic target - its application for Staphylococcus aureus detection using real-time NASBA [PDF]
A real-time nucleic acid sequence-based amplification assay, targeting tmRNA, was designed for the rapid identification of Staphylococcus aureus. The selectivity of the assay was confirmed against a panel of 76 Staphylococcus strains and species and 22 ...
Anonymous+9 more
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Quantificazione dell’enterovirus RNA mediante Nucleic Acid Sequence-Based Amplification utilizzando sonde molecular ...
Francesca Sidoti+5 more
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Slow nucleic acid unzipping kinetics from sequence-defined barriers
Recent experiments on unzipping of RNA helix-loop structures by force have shown that about 40-base molecules can undergo kinetic transitions between two well-defined `open' and `closed' states, on a timescale = 1 sec [Liphardt et al., Science 297, 733 ...
Cocco, S., Marko, J. F., Monasson, R.
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Logic devices based on nucleic acid self‐assembly
Nucleic acids are natural macromolecules with the ability to store and transmit information based on the strict base‐pairing principle. Beyond the natural nucleic acid double helixes, various DNA/RNA nanostructures with customized geometries and ...
Xuehui Xu+4 more
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Application of CRISPR/Cas Systems in the Nucleic Acid Detection of Infectious Diseases
The CRISPR/Cas system is a protective adaptive immune system against attacks from foreign mobile genetic elements. Since the discovery of the excellent target-specific sequence recognition ability of the CRISPR/Cas system, the CRISPR/Cas system has shown
Junwei Li+8 more
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