Results 61 to 70 of about 1,295,417 (401)

Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases

Frontiers in Genetics, 2014
The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3 ...
Kozo eTomita, Seisueke eYamashita
doaj   +1 more source

Mth10b, a unique member of the Sac10b family, does not bind nucleic acid. [PDF]

PLoS ONE, 2011
The Sac10b protein family is regarded as a group of nucleic acid-binding proteins that are highly conserved and widely distributed within archaea. All reported members of this family are basic proteins that exist as homodimers in solution and bind to DNA
Yan-Feng Liu, Nan Zhang, Hong-Wei Yao, Hong-Wei Yao, Xian-Ming Pan, Meng Ge   +5 more
doaj   +1 more source

Sneak peek at the tig sequences: useful sequences built from nucleic acid data [PDF]

arXiv, 2022
This manuscript is a tutorial on tig sequences that emerged after the name "contig", and are of diverse purposes in sequence bioinformatics. We review these different sequences (unitigs, simplitigs, monotigs, omnitigs to cite a few), give intuitions of their construction and interest, and provide some examples of applications.
arxiv  

tRNA Maturation: RNA Polymerization without a Nucleic Acid Template [PDF]

, 2004
The CCA-adding enzyme, which builds and repairs the 3′ terminal CCA sequence of tRNA, is the only RNA polymerase that can synthesize a defined nucleotide sequence without using a nucleic acid template. New cocrystal structures tell us how this remarkable
Weiner, Alan M.
core   +1 more source

Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions. [PDF]

PLoS ONE, 2016
Protein-nucleic acid interactions play a crucial role in the regulation of diverse biological processes. Elucidating the roles that protein-nucleic acid complexes play in the regulation of transcription, translation, DNA replication, repair and ...
Timothy A Vickers, Stanley T Crooke
doaj   +1 more source

First-principles Study of Physisorption of Nucleic Acid Bases on Small-Diameter Carbon Nanotube [PDF]

Nanotechnology 19, 125701 (2008), 2007
We report the results of our first-principles study based on density functional theory on the interaction of the nucleic acid base molecules adenine (A), cytosine (C), guanine (G), thymine (T), and uracil (U), with a single-walled carbon nanotube (CNT).
arxiv   +1 more source

Graph theoretic methods for the analysis of structural relationships in biological macromolecules [PDF]

, 2005
Subgraph isomorphism and maximum common subgraph isomorphism algorithms from graph theory provide an effective and an efficient way of identifying structural relationships between biological macromolecules.
Altschul, Artymiuk, Artymiuk, Artymiuk, Artymiuk, Artymiuk, Barnard, Baxevanis, Benning, Berman, Bernstein, Brint, Brint, Bron, Bruno, Bryant, Crandell, Dean, Diestel, Doubet, Fan, Feizi, Figueras, Flores, Gardiner, Gati, Good, Gray, Groves, Gruer, Gund, Hagadone, Harrison, Holden, Hutchinson, Jasanoff, Johnson, Kanna, Klausner, Kleywegt, Koch, Kraulis, Lengauer, Lesk, Martin, Martin, McGregor, Messmer, Mitchell, Ollis, Pickering, Ray, Raymond, Read, Salton, Samudrala, Sayle, Simon, Srere, Sussenguth, Tesmer, Tinoco, Trinajstic, Tsukada, Ullmann, van Rijsbergen, Willett, Willett, Willett, Willett, Williams, Wilson, Zhang   +72 more
core   +3 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Useful Microsoft® WordTM Macros for Molecular Biologists and Protein Chemists

BioTechniques, 2000
Biologists today make extensive use of word processing programs for the production of research reports, literature reviews and grant proposals. Frequently, such programs become the default platform for viewing and the later publication of protein and ...
Gerry Shaw
doaj   +1 more source

DNA Ligase-Mediated Translation of DNA Into Densely Functionalized Nucleic Acid Polymers [PDF]

, 2013
We developed a method to translate DNA sequences into densely functionalized nucleic acids by using T4 DNA ligase to mediate the DNA-templated polymerization of 5′-phosphorylated trinucleotides containing a wide variety of appended functional groups ...
Hili, Ryan, Liu, David Ruchien, Niu, Jia
core   +2 more sources