Results 31 to 40 of about 1,128,851 (326)

Developing Community Resources for Nucleic Acid Structures

open access: yesLife, 2022
In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has
Helen M. Berman   +2 more
doaj   +1 more source

Increasing SARS-CoV-2 nucleic acid testing capacity during the COVID-19 epidemic in Beijing: experience from a general hospital

open access: yesEmerging Microbes and Infections, 2020
Under the ongoing COVID-19 prevention and control measures in China, increasing the laboratory severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid testing capacity has become the top priority.
Qi Wang   +8 more
doaj   +1 more source

Mining of Leaf Rust Resistance Genes Content in Egyptian Bread Wheat Collection

open access: yesPlants, 2021
Wheat is a major nutritional cereal crop that has economic and strategic value worldwide. The sustainability of this extraordinary crop is facing critical challenges globally, particularly leaf rust disease, which causes endless problems for wheat ...
Mohamed A. M. Atia   +5 more
doaj   +1 more source

A Proposed Structure For The Nucleic Acids [PDF]

open access: yesProceedings of the National Academy of Sciences, 1953
The citation for the published article is: Pauling, Linus, and Robert B. Corey. "A Proposed Structure for the Nucleic Acids." Proceedings of the National Academy of Sciences 39 (1953): 84-97.
Robert B. Corey, Linus Pauling
openaire   +2 more sources

Linking molecular models with ion mobility experiments. Illustration with a rigid nucleic acid structure

open access: yesJournal of Mass Spectrometry, 2015
Ion mobility spectrometry experiments allow the mass spectrometrist to determine an ion's rotationally averaged collision cross section ΩEXP. Molecular modelling is used to visualize what ion three-dimensional structure(s) is(are) compatible with the ...
V. D’Atri   +3 more
semanticscholar   +1 more source

Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations

open access: yesScientific Reports, 2017
The bright fluorescent cytosine analogue tCO stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA.
Anders Foller Füchtbauer   +5 more
doaj   +1 more source

Modification mapping by nanopore sequencing

open access: yesFrontiers in Genetics, 2022
Next generation sequencing (NGS) has provided biologists with an unprecedented view into biological processes and their regulation over the past 2 decades, fueling a wave of development of high throughput methods based on short read DNA and RNA ...
Laura K. White, Jay R. Hesselberth
doaj   +1 more source

Molecular Dynamics Analysis of Biomolecular Systems Including Nucleic Acids [PDF]

open access: yesarXiv, 2021
Along with recent progress in structural biology and genome biology, structural dynamics of molecular systems including nucleic acids has attracted attention in the context of gene regulation. Structure-function relationship is an important topic, where physicochemical properties of nucleotides are important as well as those of amino acids in proteins.
arxiv  

Origin of Information Encoding in Nucleic Acids through a Dissipation-Replication Relation [PDF]

open access: yesEntropy 2020, 22(9), 940, 2018
Ultraviolet light incident on organic material can initiate its spontaneous dissipative structuring into chromophores which can then catalyze their own replication. This may have been the case for one of the most ancient of all chromophores dissipating the Archean UVC photon flux, the nucleic acids.
arxiv   +1 more source

Duplex Structure of a Minimal Nucleic Acid [PDF]

open access: yesJournal of the American Chemical Society, 2008
The crystal structure of an 8-mer (S)-GNA duplex is presented. As a tool for phasing, the anomalous diffraction of two copper(II) ions within two artificial metallo-base pairs was employed. The duplex structure confirms a canonical Watson-Crick base pairing scheme of GNA with antiparallel strands.
Mark K. Schlegel   +2 more
openaire   +3 more sources

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