Results 101 to 110 of about 221,973 (265)

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

open access: yesChemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

open access: yesChemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova   +2 more
wiley   +1 more source

Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells

open access: yesChemistry – A European Journal, EarlyView.
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu   +5 more
wiley   +1 more source

Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications

open access: yesChemistry – A European Journal, EarlyView.
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley   +1 more source

Dual‐State Photophysical Modulation via Bifurcated Hydrogen Bonding in a U‐Shaped Dipyridophenazine‐Cored Donor‐π‐Acceptor‐π‐Donor Fluorophore

open access: yesChemistry – A European Journal, EarlyView.
A donor–π–acceptor–π–donor (D–π–A–π–D) fluorophore bearing a U‐shaped dipyridophenazine core forms bifurcated hydrogen bonds with neutral donors such as sulfonamides or water. This interaction modulates both ground and excited states, enabling red‐shifted emission and enhanced photoluminescence in solution and solid state.
Kimiya Takei   +7 more
wiley   +1 more source

Primordial RNA Replication and Applications in PCR Technology [PDF]

open access: yes, 2013
The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is offered here based ...
Palasek, Stan
core  

Chemical engineering as an essential element of industrial biotechnology in Mexico: New aims in research and university education

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía   +3 more
wiley   +1 more source

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