Results 121 to 130 of about 215,794 (272)

3P114 Statistical Thermodynamics for Binding of an RNA Aptamer and a Partial Peptide of a Prion Protein(04. Nucleic acid binding proteins,Poster)

, 2013
Tomohiko Hayashi, Hiraku Oshima, Tsukasa Mashima, Takashi Nagata, Masato Katahira, Masahiro Kinoshita   +5 more
openalex   +2 more sources

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Peptide Nucleic Acids Containing Cationic/Amino-Alkyl Modified Bases Promote Enhanced Hybridization Kinetics and Thermodynamics with Single-Strand DNA

, 2023
Frank Podlaski, Stephen Cornwell, Kenny K. Wong, Brian A. McKittrick, Jae‐Hun Kim, Daram Jung, Yeasel Jeon, Kwang‐Bok Jung, Peter Tolias, William T. Windsor   +9 more
openalex   +1 more source

Progress in Aptamer Research and Future Applications

ChemistryOpen, EarlyView.
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu, Xiaolu Li, Huyang Gao, Jing Chen, Hongfeng Jiang   +4 more
wiley   +1 more source

Voltammmetric Assessment and Examination of the Interactions between Levetiracetam and DNA: Experimental Research, Molecular Docking, and Modeling Studies

ChemistryOpen, EarlyView.
This research introduces, for the first time, a novel, efficient, cost‐effective, and highly sensitive approach for the quantification of levetiracetam (LEV) through a differential pulse voltammetry technique based on its interaction with DNA. The method capitalizes on the changes observed in the oxidation current peak of the deoxyguanosine base, which
Abdullah Al Faysal, Pelin Şenel, Taner Erdoğan, Ayşegül Gölcü   +3 more
wiley   +1 more source

Thermodynamics of the interactions ofm-AMSA ando-AMSA with nucleic acids: influence of ionic strength and DNA base composition [PDF]

, 1989
Randy M. Wadkins, David E. Graves
openalex   +1 more source

Synergies in Self‐Assembly—From Supramolecular Polymers to Defined Hierarchical Superstructures

Journal of Polymer Science, EarlyView.
Shaping supramolecular polymers built from molecular building blocks into superstructures with defined dimensions. Synergies within supramolecular architectures such as chirality or an additional second orthogonal driving force that does not interfere with the central supramolecular motif facilitate the confinement of the growth of these ...
Klaus Kreger, Florian Behrendt, Johannes C. Brendel   +2 more
wiley   +1 more source

Functional and Structural Analyses of Diverse G‐Quadruplex and Non‐G‐Quadruplex Structures Formed by Guanine‐Rich Nucleic Acids: A Study on the Insulin Aptamer

Small, EarlyView.
IGA3, a guanine‐rich insulin aptamer, adopts different structures depending on environmental conditions. Under low cation concentrations, IGA3 forms a non‐G‐quadruplex structure that interacts with insulin. This finding highlights that guanine‐rich nucleic acids, in structures other than G‐quadruplex, can also bind to proteins, revealing valuable ...
Naoya Iwano, Taiji Oyama, Mizuki Tomizawa, Shintaro Inaba, Ryuma Mori, Yasumoto Nakazawa, Koji Sode, Kaori Tsukakoshi, Takayuki Nakano, Kazunori Ikebukuro   +9 more
wiley   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Polyethylene Glycol Nanofiller for Robust Lyophilization of Graphically Encoded Hydrogel Microparticles

Small, EarlyView.
The polyethylene glycol (PEG) nanofiller exerts a superior stabilization effect on the geometries and porous structures of the graphically encoded hydrogel microparticles in a lyophilization process. The as‐lyophilized microparticles can exert robust immunoassay performances (limit of detection: 6.48 pg mL−1) after thermal aging treatment, which ...
Wookyoung Jang, Ji Won Byun, Jun Hee Choi, Bolam Kim, Ki Wan Bong   +4 more
wiley   +1 more source