Twisting tetraplex DNA: A strand dynamics regulating i-motif function in diverse molecular crowding environments. [PDF]
Takahashi S+5 more
europepmc +1 more source
Liposomal Encapsulation in Food Systems: A Review of Formulation, Processing, and Applications
Liposomal microencapsulation stands as a promising technique for the food industry, offering versatile solutions to protect, deliver, and enhance the functionality of bioactive compounds, enzymes, and other food ingredients. This review has highlighted the fundamental aspects of liposomes, including their structure, properties, and formulation methods,
Muhammad Abdul Rahim+7 more
wiley +1 more source
Recent advances in CRISPR-based single-nucleotide fidelity diagnostics. [PDF]
Kohabir KAV+2 more
europepmc +1 more source
Applications of Artificial Intelligence in Biotech Drug Discovery and Product Development
Artificial intelligence is reshaping drug discovery by enhancing molecular design, target engagement, and therapeutic delivery with unprecedented precision and efficiency. This review summarizes recent advances in AI‐driven approaches across small molecule design, protein binder development, antibody engineering, and nanoparticle‐based delivery systems,
Yuan‐Tao Liu+14 more
wiley +1 more source
Enhancing aptamer selection in alzheimer's disease: integrating structure prediction and molecular dynamics simulations. [PDF]
Lohnes BJ+3 more
europepmc +1 more source
Cold atmospheric plasma (CAP) is a promising method for inactivating antibiotic‐resistant bacteria in liquid environments. This review explores its mechanisms, treatment parameters, and efficacy, highlighting CAP's potential as a sustainable, resistance‐free disinfection alternative and its relevance for advancing water treatment and combating ...
Manca Lunder, Sebastian Dahle, Rok Fink
wiley +1 more source
An exception or the rule? This work represents a second observation, and the first crystallographic evidence, of true intercalation of a small‐molecule ligand (here, bisquinolinium PyDH2) into an antiparallel G‐quadruplex (G4) DNA fold. Abstract G‐quadruplexes (G4s) are non‐canonical DNA structures implicated in a number of biological processes.
Kailey N. Martin+7 more
wiley +2 more sources
Predicting rare DNA conformations via dynamical graphical models: a case study of the B→A transition. [PDF]
De Silva N, Perez A.
europepmc +1 more source
Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer
Nanogel refers to nanosized particles formed by physical or chemical crosslinking of polymers. Rational design and refinement of nanogel properties are imperative to unlock their full potential, ensuring tailored solutions for personalized cancer management. This review elucidates the transformative potential of radiolabeled nanogels in revolutionizing
Sanchita Ghosh+2 more
wiley +1 more source
DNA calorimetric force spectroscopy at single base pair resolution. [PDF]
Rissone P+3 more
europepmc +1 more source