Results 161 to 170 of about 7,473,748 (355)
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.
European Journal of Biochemistry, 1974 W. Bonner, R. Laskey
semanticscholar +1 more source
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
Advanced Materials, EarlyView.As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
Advanced Materials, EarlyView.Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source
Fast quantification of nucleic acid hybrids by affinity-based hybrid collection
, 1986 A hybridization technique for the quantification of nucleic acids is described. In the method a probe pair is allowed to form hybrids with the target nucleic acid in solution.
Söderlund, H +2 more
core
Biomass DNA: An Emerging Building Block for Advanced Materials
Advanced Materials, EarlyView.Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Life‐Like Ferrous Oxide Microspheres from Kombucha
Advanced Materials Interfaces, EarlyView.Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis +2 more
wiley +1 more source
Interface Dynamics in Biomolecular Condensates by High‐Speed AFM
Advanced Materials Interfaces, EarlyView.High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria +6 more
wiley +1 more source
A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration
Advanced Materials Interfaces, EarlyView.The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani +2 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Region‐specific profiling of the gut microbiome is achieved non‐invasively using electronics‐free ingestible sampling capsules that activate at defined intestinal sites through stimuli‐responsive coatings. Deployed in a porcine dietary intervention model, the capsules resolve spatially distinct, fiber‐driven shifts in microbial composition and short ...
Devendra Sarnaik +8 more
wiley +1 more source