Results 211 to 220 of about 1,085,302 (363)

Improved Messenger RNA Stability and Biocompatibility Through Self-Gelatinizable Nucleic Acids. [PDF]

open access: yesBiotechnol Bioeng
Tanifuji T   +5 more
europepmc   +1 more source

Time‐Resolved SAXS Reveals Distinct Millisecond Metal‐Induced Conformational Dynamics of Monomeric α‐Synuclein

open access: yesAdvanced Science, EarlyView.
Time‐resolved SAXS reveals how physiologically relevant metal ions shape the earliest conformational responses of monomeric α‐synuclein. Fe3+ induces rapid compaction, Cu2+ generates heterogeneous and partially folded ensembles, while Mn2+ and Zn2+ cause only modest changes.
Rebecca Sternke‐Hoffmann   +3 more
wiley   +1 more source

Self-Avoiding Gamma Peptide Nucleic Acids for Selective Targeting of RNA Secondary Structures. [PDF]

open access: yesACS Chem Biol
Dhami I   +7 more
europepmc   +1 more source

A portable device for nucleic acid quantification powered by sunlight, a flame or electricity

open access: green, 2018
Ryan Snodgrass   +8 more
openalex   +2 more sources

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu   +9 more
wiley   +1 more source

Peptide Nucleic Acids (PNAs) in Antimicrobial Therapy: A Next Generation Strategy. [PDF]

open access: yesInt J Mol Sci
D'Aniello A   +5 more
europepmc   +1 more source

Tunable nanofluidic device for digital nucleic acid analysis

open access: bronze
Imman I. Hosseini   +6 more
openalex   +2 more sources

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

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