Results 291 to 300 of about 1,078,683 (343)

Antibody‐Functionalized DNA Hydrogels Recognize and Isolate Living Tumor Cells

Advanced Materials Interfaces, EarlyView.
We present a novel strategy using DNA Y‐motif nanostar hydrogels and DNA‐functionalized antibodies for precise live‐cell manipulation. Target cells are labeled with DNA sticky ends that hybridize with DNA Y‐motifs, enabling their incorporation and capture within the hydrogel during self‐assembly.
Laura Bourdon, Audrey Cochard, Yannick Tauran, Yoshinobu Sugitani, Yusuke Sato, Masahiro Takinoue, Hiroyuki Fujita, Teruo Fujii, Soo Hyeon Kim, Anthony J. Genot   +9 more
wiley   +1 more source

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies. [PDF]

Gels
Giordano S, Terracciano M, Gallo E, Diaferia C, Falanga AP, Accardo A, Franzese M, Salvatore M, Piccialli G, Borbone N, Oliviero G.   +10 more
europepmc   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Looking back at 20 years of Open Access publishing at Nucleic Acids Research. [PDF]

Nucleic Acids Res
Roberts R.
europepmc   +1 more source

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

Advanced Materials Technologies, EarlyView.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha, Zeqi Niu, Abha Kumari, Scott Smith, Grace Li, Kruthi Srinivasa Raju, Joseph Marvar, Thomas Leekley, Shawn Fortna, Yoon‐Tae Kang, Sunitha Nagrath   +10 more
wiley   +1 more source

Cobra Three-Finger Toxins Interact with RNA and DNA: Nucleic Acids as Their Putative Biological Targets. [PDF]

Int J Mol Sci
Osipov AV, Starkov VG, Tsetlin VI, Utkin YN.   +3 more
europepmc   +1 more source

Advances in Optical Techniques for Tumor Detection

Advanced Optical Materials, EarlyView.
Cancer detection is vital for patient survival. Optical technologies overcome conventional cytology's limitations with high sensitivity and molecular specificity. This review highlights five techniques: Raman spectroscopy, fluorescence sensors, fiber optic sensors, photoacoustic imaging, and colorimetric detection for tumor diagnosis via direct ...
Yang Yu, Anqi Yang, Jiaqi Liao, Julian Evans, Ruili Zhang, Shuang E, Sailing He   +6 more
wiley   +1 more source

Circular Nucleic Acids Act as an Oncogenic MicroRNA Sponge to Inhibit Hepatocellular Carcinoma Progression. [PDF]

Biomedicines
Zhang Q, Sun P, Hu G, Yu X, Zhang W, Feng X, Yu L, Zhang P.   +7 more
europepmc   +1 more source

Linker‐Free Covalent DNA Functionalization of Quantum‐Grade Nanodiamonds

Advanced Optical Materials, EarlyView.
Nanodiamond (ND) surface is terminated with azide groups via nucleophilic substitution and decarboxylative azidation. The resulting azidated NDs display high click reactivity while retaining the spin and charge properties of nitrogen‐vacancy centers.
Jakub Copak, Filip Steiner, Ema Fialova, Tomas Matousek, Jan Plutnar, David Chvatil, Michal Gulka, Petr Cigler   +7 more
wiley   +1 more source

Selenium-functionalized hyaluronic acid dissolvable microneedle patch synergistic herbal shikonin-loaded tetrahedral framework nucleic acids for psoriasis therapy. [PDF]

Mater Today Bio
Zhuo M, Cheng N, Du J, Wang T, Sun C, Lu S, Wang J, Ding D.   +7 more
europepmc   +1 more source