Results 271 to 280 of about 516,976 (317)
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Current Protocols in Cytometry, 2003
AbstractThis unit describes the physicochemical structures of commonly used nucleic acid probes, classified into four groups based on their mode of nucleic acid binding. The unit provides an excellent background for the many protocols employing these dyes and should be a prerequisite for any studies involving nuclear probes.
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AbstractThis unit describes the physicochemical structures of commonly used nucleic acid probes, classified into four groups based on their mode of nucleic acid binding. The unit provides an excellent background for the many protocols employing these dyes and should be a prerequisite for any studies involving nuclear probes.
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Nucleic acids and polynucleotides
Journal of Cellular Physiology, 1969The conformation of native double helical DNA is well-known, but it is possible that small regions occur within native DNA, undetectable by X-ray diffraction methods, which have different conformations. Model structures are the synthetic deoxypolynucleotides of defined sequence. Under the conditions used, DNA, poly d(A-T) • poly d(A-T), and poly d(T-G)
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Current Protocols in Immunology, 1998
AbstractThis unit provides protocols for two broadly used methods of DNA immunization: saline injections and gene gun deliveries of DNA. Saline injections deliver DNA into extracellular spaces; gene gun deliveries bombard DNA directly into cells.
H L, Robinson, T M, Pertmer
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AbstractThis unit provides protocols for two broadly used methods of DNA immunization: saline injections and gene gun deliveries of DNA. Saline injections deliver DNA into extracellular spaces; gene gun deliveries bombard DNA directly into cells.
H L, Robinson, T M, Pertmer
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Nucleic acids in the environment
Current Opinion in Biotechnology, 1996The past year has witnessed several excellent advances in basic and applied research on nucleic acids in the environment. Improved methods for extracting nucleic acids from environmental samples have been published, as well as information on the use of reporter genes in bacteria, natural genetic transformation in soil and DNA adsorption to soil.
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2005
Saccharomyces cerevisiae is an excellent model organism for the study of eukaryotic genetics. Easy manipulation of yeast DNA is essential to its role in research, and studies of gene expression or regulation require analysis of RNA. This chapter presents quick and straightforward methods to isolate genomic DNA, plasmid DNA, or RNA from yeast.
Michelle, Hanna, Wei, Xiao
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Saccharomyces cerevisiae is an excellent model organism for the study of eukaryotic genetics. Easy manipulation of yeast DNA is essential to its role in research, and studies of gene expression or regulation require analysis of RNA. This chapter presents quick and straightforward methods to isolate genomic DNA, plasmid DNA, or RNA from yeast.
Michelle, Hanna, Wei, Xiao
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1967
Publisher Summary Not only can antibodies against DNA be found in various autoimmune diseases, but DNA, RNA, various oligonucleotides, and even mono-nucleosides can be immunogenic under suitable conditions or when complexed with carriers such as methylated bovine serum albumin. This chapter reviews the development of the antigenicity of nucleic acids
O J, Plescia, W, Braun
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Publisher Summary Not only can antibodies against DNA be found in various autoimmune diseases, but DNA, RNA, various oligonucleotides, and even mono-nucleosides can be immunogenic under suitable conditions or when complexed with carriers such as methylated bovine serum albumin. This chapter reviews the development of the antigenicity of nucleic acids
O J, Plescia, W, Braun
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Current Opinion in Biotechnology, 2005
Since the discovery of the first natural ribozyme more than 20 years ago, it has become clear that nucleic acids are not only the static depository of genetic information, but also possess intriguing catalytic activity. The number of reactions catalyzed by engineered nucleic acid enzymes is growing continuously.
Fiammengo, R., Jaschke, A.
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Since the discovery of the first natural ribozyme more than 20 years ago, it has become clear that nucleic acids are not only the static depository of genetic information, but also possess intriguing catalytic activity. The number of reactions catalyzed by engineered nucleic acid enzymes is growing continuously.
Fiammengo, R., Jaschke, A.
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The American Journal of Medicine, 1963
I N 1953 Watson and Crick [I] proposed a model for the structure and replication of DNA and in doing so inaugurated the science known as molecular biology. In the intervening ten years, advance in this subject has been spectacular. It can now be seen that the general principles which govern the controlled functioning and self-replication of living ...
C I, DAVERN, J, CAIRNS
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I N 1953 Watson and Crick [I] proposed a model for the structure and replication of DNA and in doing so inaugurated the science known as molecular biology. In the intervening ten years, advance in this subject has been spectacular. It can now be seen that the general principles which govern the controlled functioning and self-replication of living ...
C I, DAVERN, J, CAIRNS
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1953
Publisher Summary The history of the study of the nucleic acids has in fact been a tragic-comedy of the application of drastic methods to materials that in many ways are less stable than most proteins and are also susceptible to attack by a large number of enzymes, many of which are extremely stable and most of which are widely distributed.
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Publisher Summary The history of the study of the nucleic acids has in fact been a tragic-comedy of the application of drastic methods to materials that in many ways are less stable than most proteins and are also susceptible to attack by a large number of enzymes, many of which are extremely stable and most of which are widely distributed.
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