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Precision Control of Light-Responsive Nucleic Acids Modified with Photoremovable Protecting Groups for Functionalization. [PDF]
JACS AuZhou Z, Chan HY, Lo PK.
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Nucleic acids delivering nucleic acids
Advanced Drug Delivery Reviews, 2018Nucleic acid therapeutics, including siRNAs, miRNAs/antimiRs, gRNAs and ASO, represent innovative and highly promising molecules for the safe treatment of a wide range of pathologies. The efficiency of systemic treatments is impeded by 1) the need to overcome physical and functional barriers in the organism, and 2) to accumulate in the intracellular ...
Catuogno S +3 more
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Journal of the American Chemical Society, 2012
A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This Perspective details the synthetic methods for preparing them, followed by a discussion of their unique properties and theoretical and experimental models for understanding them.
Joshua I, Cutler +2 more
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A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This Perspective details the synthetic methods for preparing them, followed by a discussion of their unique properties and theoretical and experimental models for understanding them.
Joshua I, Cutler +2 more
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Annual Review of Biochemistry, 1957
Recent work in the fields of nucleic acid structure, the relation of nucleic acids to physiological and metabolic events, and biological interventions are summarized. (C.H.)
W E, COHN, E, VOLKIN
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Recent work in the fields of nucleic acid structure, the relation of nucleic acids to physiological and metabolic events, and biological interventions are summarized. (C.H.)
W E, COHN, E, VOLKIN
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Current Opinion in Chemical Biology, 1999
Last year provided new structural data, particularly for the group I intron and the Hepatitis delta ribozymes, that were essential for a better understanding of the RNA structure/function relationship. The role of metal ions in catalysis of ribozyme action still remains elusive, however.
C, Carola, F, Eckstein
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Last year provided new structural data, particularly for the group I intron and the Hepatitis delta ribozymes, that were essential for a better understanding of the RNA structure/function relationship. The role of metal ions in catalysis of ribozyme action still remains elusive, however.
C, Carola, F, Eckstein
openaire +2 more sources