Results 311 to 320 of about 1,094,037 (343)
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Journal of the American Chemical Society, 2012
A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This Perspective details the synthetic methods for preparing them, followed by a discussion of their unique properties and theoretical and experimental models for understanding them.
Joshua I, Cutler +2 more
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A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This Perspective details the synthetic methods for preparing them, followed by a discussion of their unique properties and theoretical and experimental models for understanding them.
Joshua I, Cutler +2 more
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Nature, 1952
Smith and Stoker1 have noted that the deoxyribonucleic acid of Q-fever rickettsiae (R. burneti) grown in embryonated eggs is closely similar in composition to that of chick embryos, the only significant difference being lack of 5-methyl cytosine from the former.
G R, WYATT, S S, COHEN
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Smith and Stoker1 have noted that the deoxyribonucleic acid of Q-fever rickettsiae (R. burneti) grown in embryonated eggs is closely similar in composition to that of chick embryos, the only significant difference being lack of 5-methyl cytosine from the former.
G R, WYATT, S S, COHEN
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1967
Publisher Summary Not only can antibodies against DNA be found in various autoimmune diseases, but DNA, RNA, various oligonucleotides, and even mono-nucleosides can be immunogenic under suitable conditions or when complexed with carriers such as methylated bovine serum albumin. This chapter reviews the development of the antigenicity of nucleic acids
O J, Plescia, W, Braun
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Publisher Summary Not only can antibodies against DNA be found in various autoimmune diseases, but DNA, RNA, various oligonucleotides, and even mono-nucleosides can be immunogenic under suitable conditions or when complexed with carriers such as methylated bovine serum albumin. This chapter reviews the development of the antigenicity of nucleic acids
O J, Plescia, W, Braun
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2005
Saccharomyces cerevisiae is an excellent model organism for the study of eukaryotic genetics. Easy manipulation of yeast DNA is essential to its role in research, and studies of gene expression or regulation require analysis of RNA. This chapter presents quick and straightforward methods to isolate genomic DNA, plasmid DNA, or RNA from yeast.
Michelle, Hanna, Wei, Xiao
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Saccharomyces cerevisiae is an excellent model organism for the study of eukaryotic genetics. Easy manipulation of yeast DNA is essential to its role in research, and studies of gene expression or regulation require analysis of RNA. This chapter presents quick and straightforward methods to isolate genomic DNA, plasmid DNA, or RNA from yeast.
Michelle, Hanna, Wei, Xiao
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Current Opinion in Chemical Biology, 1999
Last year provided new structural data, particularly for the group I intron and the Hepatitis delta ribozymes, that were essential for a better understanding of the RNA structure/function relationship. The role of metal ions in catalysis of ribozyme action still remains elusive, however.
C, Carola, F, Eckstein
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Last year provided new structural data, particularly for the group I intron and the Hepatitis delta ribozymes, that were essential for a better understanding of the RNA structure/function relationship. The role of metal ions in catalysis of ribozyme action still remains elusive, however.
C, Carola, F, Eckstein
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Current Opinion in Biotechnology, 2005
Since the discovery of the first natural ribozyme more than 20 years ago, it has become clear that nucleic acids are not only the static depository of genetic information, but also possess intriguing catalytic activity. The number of reactions catalyzed by engineered nucleic acid enzymes is growing continuously.
Fiammengo, R., Jaschke, A.
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Since the discovery of the first natural ribozyme more than 20 years ago, it has become clear that nucleic acids are not only the static depository of genetic information, but also possess intriguing catalytic activity. The number of reactions catalyzed by engineered nucleic acid enzymes is growing continuously.
Fiammengo, R., Jaschke, A.
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Nucleic acids and polynucleotides
Journal of Cellular Physiology, 1969The conformation of native double helical DNA is well-known, but it is possible that small regions occur within native DNA, undetectable by X-ray diffraction methods, which have different conformations. Model structures are the synthetic deoxypolynucleotides of defined sequence. Under the conditions used, DNA, poly d(A-T) • poly d(A-T), and poly d(T-G)
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Current Protocols in Cytometry, 2003
AbstractThis unit describes the physicochemical structures of commonly used nucleic acid probes, classified into four groups based on their mode of nucleic acid binding. The unit provides an excellent background for the many protocols employing these dyes and should be a prerequisite for any studies involving nuclear probes.
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AbstractThis unit describes the physicochemical structures of commonly used nucleic acid probes, classified into four groups based on their mode of nucleic acid binding. The unit provides an excellent background for the many protocols employing these dyes and should be a prerequisite for any studies involving nuclear probes.
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The American Journal of Medicine, 1963
I N 1953 Watson and Crick [I] proposed a model for the structure and replication of DNA and in doing so inaugurated the science known as molecular biology. In the intervening ten years, advance in this subject has been spectacular. It can now be seen that the general principles which govern the controlled functioning and self-replication of living ...
C I, DAVERN, J, CAIRNS
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I N 1953 Watson and Crick [I] proposed a model for the structure and replication of DNA and in doing so inaugurated the science known as molecular biology. In the intervening ten years, advance in this subject has been spectacular. It can now be seen that the general principles which govern the controlled functioning and self-replication of living ...
C I, DAVERN, J, CAIRNS
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Biochimie, 1973
Summary Present knowledge about the structure and function of mtDNA and its transcription products is briefly discussed with special emphasis on the unusual structure of mtDNA in Tetrahymena pyriformis and recent experiments on the possible import of mRNA into mitochondria.
P, Borst, L A, Grivell
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Summary Present knowledge about the structure and function of mtDNA and its transcription products is briefly discussed with special emphasis on the unusual structure of mtDNA in Tetrahymena pyriformis and recent experiments on the possible import of mRNA into mitochondria.
P, Borst, L A, Grivell
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