Results 311 to 320 of about 6,062,195 (387)

Synthesis of Tertiary Amine Assisted Cytocompatible Zn‐MOFs for Efficient Nucleic Acid Encapsulation and Delivery to Prostate Cancer Cells

Advanced Materials Interfaces, EarlyView.
The study explores the influence of a tertiary amine in loading genetic material in a hybrid composite. The study highlights how structural attributes and chemical composition govern the crystallinity and cytocompatibility of ZIF‐biocomposites that effectively deliver nucleic acid to cancer cells.
Shakil Ahmed Polash, Gary Bryant, Vipul Bansal, Ravi Shukla   +3 more
wiley   +1 more source

Comparative evaluation of proteinase K and dithiothreitol as pretreatments for extracting nucleic acids from respiratory samples for multiplex PCR. [PDF]

BMC Microbiol
Chang Y, Li T, Niu Y, Guan X, Xie Y.
europepmc   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Structure-Guided design of Cas12a variants improves detection of nucleic acids. [PDF]

Cell Insight
Tong X, Li T, Zhang K, Zhao D, Zhang Y, Yin H.   +5 more
europepmc   +1 more source

Transcript Identification Using Arrayed Hydrogels With TrapFISH

Advanced Materials Technologies, EarlyView.
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse, Zenon Toprakcioglu, Akhila Denduluri‐Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles   +5 more
wiley   +1 more source

Exploring Framework Nucleic Acids: A Perspective on Their Cellular Applications. [PDF]

JACS Au
Wang Z, Wang X, He Y, Wu H, Mao R, Wang H, Qiu L.   +6 more
europepmc   +1 more source

Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)

Advanced Materials Technologies, EarlyView.
A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha, Zeqi Niu, Abha Kumari, Scott Smith, Grace Li, Kruthi Srinivasa Raju, Joseph Marvar, Thomas Leekley, Shawn Fortna, Yoon‐Tae Kang, Sunitha Nagrath   +10 more
wiley   +1 more source

Direct SERS Detection of Nucleic Acids in the Presence of Spermine: A Unified Nanoparticle Platform Allows for the Elucidation of Surface Adsorption Hierarchies. [PDF]

J Phys Chem C Nanomater Interfaces
Deriu C, Fabris L.
europepmc   +1 more source

Bioelectronic Sensors for Neuromuscular Perception in Human‐Machine Interfaces

Advanced Robotics Research, EarlyView.
This review summarizes recent advances in bioelectronic sensors for neuromuscular perception in human‐machine interfaces. By integrating biopotential, electrical impedance, and electrochemical sensing strategies with flexible electrode interfaces, these bioelectronic sensing systems enable intuitive, real‐time detection of muscle and nerve activity ...
Junwei Li, Bangyan Niu, Kunlin Wu, Jingcheng Xiao, Xiaoyan Liu, Yifan Wang   +5 more
wiley   +1 more source