Results 81 to 90 of about 7,455 (179)
A pelagic microbiome (viruses to protists) from a small cup of seawater [PDF]
, 2017 The aquatic microbiome is composed of a multi-phylotype community of microbes, ranging from the numerically dominant viruses to the phylogenetically diverse unicellular phytoplankton.
Cecilia Balestreri +10 more
core +2 more sources
IET Systems Biology, Volume 20, Issue 1, January/December 2026.This study identified an eight‐gene signature associated with SUMOylation using machine learning and bioinformatics approaches, which effectively stratifies sepsis patients into two distinct subtypes: immune‐suppressive and hyper‐inflammatory. This discovery not only reveals the critical role of SUMOylation in sepsis heterogeneity but also provides new
Zeqian Li +8 more
wiley +1 more source
VirusesAfrican swine fever virus (ASFV) belongs to the family of Asfarviridae, part of the group of nucleocytoplasmic large DNA viruses (NCLDV). Little is known about the internalization of ASFV in the host cell and the fusion membrane events that take place at
Jesús Urquiza +6 more
doaj +1 more source
Cedratvirus lausannensis - digging into Pithoviridae diversity. [PDF]
, 2017 Amoeba-infecting viruses have raised scientists' interest due to their novel particle morphologies, their large genome size and their genomic content challenging previously established dogma.
Bertelli, C. +5 more
core +1 more source
TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models
The FEBS Journal, Volume 293, Issue 2, Page 348-384, January 2026.The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir +7 more
wiley +1 more source
Immunogenicity of DNA Vaccine against H5N1 Containing Extended Kappa B Site: In Vivo Study in Mice and Chickens [PDF]
, 2017 Influenza is one of the most important illnesses in the modern world, causing great public health losses each year due to the lack of medication and broadly protective, long-lasting vaccines.
Bocian, Katarzyna +6 more
core +2 more sources
BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43
Advanced Science, Volume 12, Issue 45, December 4, 2025.This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan +13 more
wiley +1 more source
Antarctic Marine Viruses: A Review and Future Perspectives
Ocean-Land-Atmosphere ResearchThis review synthesizes recent research on how Antarctic marine viruses influence polar ecosystems, focusing on their distribution, diversity, and ecological roles.
Chuan Zhai +4 more
doaj +1 more source
DNA transposons have colonized the genome of the giant virus Pandoravirus salinus [PDF]
, 2015 BACKGROUND: Transposable elements are mobile DNA sequences that are widely distributed in prokaryotic and eukaryotic genomes, where they represent a major force in genome evolution.
Cheng Sun +3 more
core +1 more source
Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders
Advanced Science, Volume 12, Issue 47, December 18, 2025.This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin +8 more
wiley +1 more source