MSystems, 2021 Viruses belonging to the Nucleocytoviricota phylum are globally distributed and include members with notably large genomes and complex functional repertoires.
Anh D. Ha +2 more
exaly +3 more sources
Epigenome analysis of an algae-infecting giant virus reveals a unique methylation motif catalogue. [PDF]
PLoS ONEDNA methylation can epigenetically alter gene expression and serve as a mechanism for genomic stabilization. Advancements in long-read sequencing technology have allowed for increased exploration into the methylation profiles of various organisms ...
Alexander R Truchon +2 more
doaj +2 more sources
Grazing on Marine Viruses and Its Biogeochemical Implications [PDF]
mBio, 2023 Viruses are the most abundant biological entities in the ocean and show great diversity in terms of size, host specificity, and infection cycle. Lytic viruses induce host cell lysis to release their progeny and thereby redirect nutrients from higher to ...
Kyle M. J. Mayers +5 more
doaj +4 more sources
Giant Viruses as a Source of Novel Enzymes for Biotechnological Application
Pathogens, 2022 The global demand for industrial enzymes has been increasing in recent years, and the search for new sources of these biological products is intense, especially in microorganisms.
Joao Victor Rodrigues Pessoa Carvalho +2 more
exaly +3 more sources
From Mimivirus to Mirusvirus: The Quest for Hidden Giants
Viruses, 2023 Our perception of viruses has been drastically evolving since the inception of the field of virology over a century ago. In particular, the discovery of giant viruses from the Nucleocytoviricota phylum marked a pivotal moment.
Morgan Gaia
exaly +3 more sources
Revisiting giant virus-host dynamics in brown algae: old stories and new perspectives [PDF]
The EMBO JournalThe recent discovery of widespread giant virus sequences integrated into the genomes of diverse eukaryotes, and in particular marine lineages, has reignited interest in the molecular mechanisms underlying giant virus–host interactions.
Carole Duchêne +2 more
doaj +2 more sources
Evolutionarily conserved grammar rules viral factories of amoeba-infecting members of the hyperdiverse <i>Nucleocytoviricota</i> phylum. [PDF]
Proc Natl Acad Sci U S ADespite sharing fewer than 10 core genes, the hyperdiverse Nucleocytoviricota phylum (ranging from poxviruses to giant viruses) universally assembles viral factories (VFs) resembling biomolecular condensates. Regardless, it is unclear how these viruses achieve such a level of functional conservation without clear ...
Rigou S +16 more
europepmc +2 more sources
Tiny giants in a big ocean [PDF]
Microbiology SpectrumPrasinoviruses infect some of the most abundant photosynthetic eukaryotes in the ocean, shaping microbial dynamics and playing a major role in nutrient cycling.
Victoria F. Queiroz +2 more
doaj +2 more sources
Viral dynamics in a high-rate algal pond reveals a burst of Phycodnaviridae diversity correlated with episodic algal mortality [PDF]
mBioThis study explores virus-host dynamics in a unique environment: an industrial high-rate algal pond (HRAP). A wealth of novel DNA algal viruses are revealed, including members of Nucleocytoviricota “giant viruses” and the enigmatic Preplasmiviricota (e.g.
E. E. Chase +7 more
doaj +2 more sources
Structural dissection of vaccinia G9 identifies residues essential for membrane fusion and complex assembly [PDF]
Journal of VirologyVaccinia virus, a prototypical poxvirus, utilizes a unique multi-protein entry fusion complex (EFC), comprising 11 components, to mediate membrane fusion during host cell entry.
Hsiao-Jung Chiu +2 more
doaj +2 more sources