Results 171 to 180 of about 12,341 (216)
Repeat-element RNAs integrate a neuronal growth circuit.
Zahavi EE +31 more
europepmc +1 more source
Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons. [PDF]
Gerónimo-Olvera C +20 more
europepmc +1 more source
Characterization of nucleolin K88 acetylation defines a new pool of nucleolin colocalizing with pre‐mRNA splicing factors [PDF]
Nucleolin and SC35 colocalize by fluorescence microscopy (View interaction)
Sadhan Das +2 more
exaly +4 more sources
Glycosilated nucleolin as marker for human gliomas
AbstractNucleolin is a multifunctional DNA and RNA binding protein involved in regulation of gene transcription, chromatin remodeling, RNA metabolism, and ribosomal RNA synthesis. Nucleolin seems to be over‐expressed in highly proliferative cells and is involved in many aspect of gene expression: DNA recombination and replication, RNA transcription by ...
Renato Galzio +2 more
exaly +7 more sources
Nucleolin Overexpression Confers Increased Sensitivity to the Anti-Nucleolin Aptamer, AS1411 [PDF]
AS1411 is an antiproliferative DNA aptamer, which binds the ubiquitous protein, nucleolin. In this study, we show that constitutive overexpression of nucleolin confers increased sensitivity to the growth inhibitory effects of AS1411. HeLa cells overexpressing nucleolin have an increased growth rate and invasiveness relative to control cells.
Vivek R Sharma +2 more
exaly +3 more sources
The new face of nucleolin in human melanoma
Nucleolin is multifunctional protein mainly present in nucleoli but also detected in cytoplasm and plasma membranes. Extranuclear nucleolin differs from the nuclear form by its glycosylation. Studies on expression of nucleolin in breast cancer suggest a possible association to the metastatic cascade.
Dorota Hoja-Łukowicz +2 more
exaly +4 more sources
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Structure and functions of nucleolin
Journal of Cell Science, 1999ABSTRACT Nucleolin is an abundant protein of the nucleolus. Nucleolar proteins structurally related to nucleolin are found in organisms ranging from yeast to plants and mammals. The association of several structural domains in nucleolin allows the interaction of nucleolin with different proteins and RNA sequences.
Ginisty, H. +3 more
openaire +3 more sources
A tRF nucleator for Nucleolin in cancer metastasis
Molecular Cell, 2022In this issue of Molecular Cell, Liu et al. (2022) report that 5'-tRFCys, a stress-induced transfer RNA-derived RNA fragment (tRF) derived from the 5' halves of cysteine tRNAs, regulates post-transcriptional gene expression, enabling the survival and lung metastasis formation of breast cancers.
Yichen, Xu, Davide, Ruggero
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