Results 91 to 100 of about 72,696 (188)

The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals. [PDF]

Int J Mol Sci
Ponti D.
europepmc   +1 more source

Membraneless Organelles and Phase Separation in Tumours: Mechanisms and Prospects

Cell Proliferation, EarlyView.
The Salient and Novel Findings: This article summarises the latest research advancements in phase separation within tumours, with a particular focus on the role and molecular mechanisms of liquid–liquid phase separation (LLPS) in tumour progression.
Hao Yang, Zhong Chu, Shuwen Han, Yuefen Pan   +3 more
wiley   +1 more source

HTLV-I Basic Leucine Zipper Factor (sHBZ) Actively Associates with Nucleophosmin (B23) in the Nucleolus. [PDF]

Viruses
Moghadam N, Xiao Y, Dragon F, Barbeau B.
europepmc   +1 more source

IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target

Cell Proliferation, EarlyView.
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li, Yunpeng Zou, Jiayao Niu, Ying Zhang, Aohua Yang, Wenyu Lin, Jie Guo, Shuya Wang, Ronghan Liu   +8 more
wiley   +1 more source

The <i>Schizosaccharomyces pombe</i> nucleolar protein Nsk1 modulates rDNA silencing during interphase. [PDF]

MicroPubl Biol
Chen JS, Hanna SM, Willet AH, Gould KL.
europepmc   +1 more source

Hypertranscription of rDNA Responsible for Nucleolar Remodelling is a Doorman for Acquiring Pluripotency

Cell Proliferation, EarlyView.
Active nucleoli have the capability to release perinuclear heterochromatin, which is a novel event of iPSC reprogramming. ABSTRACT Ribosome biogenesis occurs within the nucleolus, with the initial step being the transcription of ribosomal DNA (rDNA). Although rDNA transcription is limited in somatic cells, it is more active in stem cells. Nevertheless,
Yuchen Sun, Xinglin Hu, Xingwei Huang, Wenyao Zhou, Shubing Lan, Hui Zhang, Guangming Wu, Lei Lei   +7 more
wiley   +1 more source

Nucleolar origins: challenging perspectives on evolution and function. [PDF]

Open Biol
Muñoz-Velasco I, Herrera-Escamilla AK, Vázquez-Salazar A.   +2 more
europepmc   +1 more source

Grading Melanocytic Dysplasia: Updated Histopathologic Criteria

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO‐C). WHO‐C presents a dichotomous classification (high‐grade versus low‐grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement.
Christopher R. Shea, Victor G. Prieto, Catherine M. Shachaf, Scott R. Florell   +3 more
wiley   +1 more source

<i>Snora54</i> negatively regulates self-renewal of intestinal stem cells and gut regeneration via suppression of Notch2 signaling. [PDF]

Sci Adv
Zhang J, Guo H, Xu Y, Xiong Z, Du Y, Zhu P, Fan Z.   +6 more
europepmc   +1 more source

Multiple intracranial hemorrhages in a postmenopausal female

Brain Pathology, EarlyView.
Xinhua Lu, Xinya Xu, Xiaopeng Zhang
wiley   +1 more source