Results 81 to 90 of about 63,252 (284)

A geometric chracterization of the nucleolus of the assignment game [PDF]

core, assignment games, nucleolus, cooperative games ...
Francesc Llerena, Marina Nunez, Carles Rafels   +2 more
core  

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

The Trypanosoma cruzi metacyclic-specific protein Met-III associates with the nucleolus and contains independent amino and carboxyl terminal targeting elements. [PDF]

, 2007
Metacyclogenesis in Trypanosoma cruzi involves the differentiation of replicating non-infective epimastigotes into non-replicating metacyclic trypomastigotes.
Gluenz, E, Taylor, Martin C., Gluenz, Eva, Taylor, MC, Kelly, John M., Kelly, JM, Kelly, John M, Taylor, Martin C   +7 more
core   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice

Advanced NanoBiomed Research, EarlyView.
Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin, Benjamin Chacon, Gulnaz Gahramanova, Inna Chorna, Zhanna Klishchova, Anastasia Konieva, Ilya Yanko, Andrii Liutyi, Milena Yalyzhko, Ivan Baginskiy, Veronika Zahorodna, Júlio Sílvio de Sousa Bueno Filho, Erfan Rezvani Ghomi, Igor Panko, Tetiana Shapochka, Oksana Sulaieva, Oleksandr Solodovnyk, Lucia Gemma Delogu, Oleksiy Gogotsi, Laura Fusco, Sergiy Kyrylenko, Yury Gogotsi, Maksym Pogorielov   +22 more
wiley   +1 more source

Single-cell laser emitting cytometry for label-free nucleolus fingerprinting

Nature Communications
The nucleolus, a recognized biomolecular condensate, serves as the hub for ribosome biogenesis within the cell nucleus. Its quantity and morphology are discernible indicators of cellular functional states.
Guocheng Fang, Zhen Qiao, Luqi Huang, Hui Zhu, Jun Xie, Tian Zhou, Zhongshu Xiong, I-Hsin Su, Dayong Jin, Yu-Cheng Chen   +9 more
doaj   +1 more source

Rna Buffering Fluorogenic Probe for Nucleolar Morphology Stable Imaging And Nucleolar Stress‐Generating Agents Screening

Advanced Science
In the realm of cell research, membraneless organelles have become a subject of increasing interest. However, their ever‐changing and amorphous morphological characteristics have long presented a formidable challenge when it comes to studying their ...
Wenchao Jiang, Qinglong Qiao, Jie Chen, Pengjun Bao, Yi Tao, Yinchan Zhang, Zhaochao Xu   +6 more
doaj   +1 more source

REBELOTE, a regulator of floral determinacy in Arabidopsis thaliana, interacts with both nucleolar and nucleoplasmic proteins

FEBS Open Bio, 2018
The nucleoplasm and nucleolus are the two main territories of the nucleus. While specific functions are associated with each of these territories (such as mRNA synthesis in the nucleoplasm and ribosomal rRNA synthesis in the nucleolus), some proteins are
Stève de Bossoreille, Patrice Morel, Christophe Trehin, Ioan Negrutiu   +3 more
doaj   +1 more source

An Algorithm for the Nucleolus of Airport Profit Problems [PDF]

Airport profit games are a generalization of airport cost games as well as of bankruptcy games.In this paper we present a simple algorithm to compute the nucleolus of airport profit games.In addition we prove that there exists an unique consistent ...
Brânzei, R., Tijs, S.H., Zarzuelo, J., Inarra, E.   +3 more
core  

Nucleolar localization of influenza A NS1: striking differences between mammalian and avian cells [PDF]

, 2010
In mammalian cells, nucleolar localization of influenza A NS1 requires the presence of a C-terminal nucleolar localization signal. This nucleolar localization signal is present only in certain strains of influenza A viruses.
Soubies, S.M., Mazel-Sanchez, Béryl, Sébastien M Soubies, Mazel-Sanchez, B, Jean-Luc Guérin, Volmer Christelle, Christelle Volmer, Soubiès, Sébastien, Volmer, C, Guérin Jean-Luc, Romain Volmer, Mazel-Sanchez Beryl, Nazel-Sanchez, Beryl, Guérin, Jean-Luc, Soubies Sébastien M, Volmer, Christelle, Volmer Romain, Beryl Mazel-Sanchez, Volmer, Romain   +18 more
core   +1 more source