Results 61 to 70 of about 51,957 (163)

Systematic analysis of A-to-I RNA editing upon release of ADAR from the nucleolus

RNA Biology
Adenosine-to-inosine (A-to-I) RNA editing, catalysed by two ADAR isoforms (p110 and p150) and ADARB1, is a critical regulatory step in gene expression.
Ruben Lattuca, Rümeyza Bascetin, Vincent Detours, Denis L. J. Lafontaine   +3 more
doaj   +1 more source

HAND2 invades nucleolar condensates to pioneer lineage-specific cardiac pacemaker gene programs

Nature Communications
Although best known as the site for ribosome assembly, the nucleolus organizes heterochromatin into transcriptionally repressed Nucleolus-Associated Domains (NADs).
Kartik Kulkarni, Gabriella Quinn, Jared Dela Rosa, Sean Goetsch, Vrushali Pandit, Lin Wang, Akane Sakaguchi, Sushama Sivakumar, Nikhil V. Munshi   +8 more
doaj   +1 more source

Epigenetic modifications of 45S rDNA associates with the disruption of nucleolar organisation during Cd stress response in Pakchoi

Ecotoxicology and Environmental Safety
The role of the nucleolus in Pakchoi response to Cd stress remains largely unknown. In this work, we focus on exploring the underling mechanism between nucleolus disruption and epigenetic modification in Cd stressed-Pakchoi.
Yan Xiang, Ming Zhang, Yuanfeng Hu, Liangdeng Wang, Xufeng Xiao, Fengrui Yin, Xiaoqun Cao, Meilan Sui, Yuekeng Yao   +8 more
doaj   +1 more source

Circannual Cycle of the Sertoli Cell Nucleolus in Roe Deer, Capreolus capreolus, and Seasonal Changes of Its Leydig Cells: An Ultrastructural Study

Folia Veterinaria
Ruminant Sertoli cells, instead of a nucleolus with nucleolonema, have a vesicular nucleolus, first described as a multivesicular nuclear body (MNB). It consists of membrane vesicles and tubules covered with ribo-some-like granules. We studied the testes
Zibrín Martin, Holovská Katarína, Pivko Juraj   +2 more
doaj   +1 more source

Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization

Open Biology
The nucleolus is the most prominent liquid droplet-like membrane-less organelle in mammalian cells. Unlike the nucleolus in terminally differentiated somatic cells, those in totipotent cells, such as murine zygotes or two-cell embryos, have a unique ...
Bo Fu, Hong Ma, Di Liu
doaj   +1 more source

https://www.emjreviews.com/allergy-immuThe 'Nucleolus' Hypothesis of Autoimmune Diseases and Its Implications

European Medical Journal, 2017
Many autoimmune diseases, such as lupus and Sjögren’s syndrome, have a female bias and adult onset. One possible explanation for this bias is disruption of the inactive X chromosome, which is a major epigenetic feature in female cells. Indeed, only one X
Wesley H. Brooks, Yves Renaudineau
doaj  

mTOR-NAA10-C7orf50 axis senses nutritional status to coordinate ribosome biogenesis and autophagy. [PDF]

Sci Adv
Sun J, Yang M, Li Q, Liang J, Feng H, Gao L, Wang Y, Liu H, Guo C, Tang TS.   +9 more
europepmc   +1 more source

Nucleolar expansion: A biomolecular condensate mortality timer. [PDF]

Geromedicine
Gutierrez JI, Tyler JK.
europepmc   +1 more source

Making order from disorder in the nucleolus. [PDF]

Genes Dev
Baserga SJ.
europepmc   +1 more source

Stress-induced nucleolar rejuvenation via chaperone-mediated segregation in a filamentous fungus. [PDF]

J Cell Biol
Rogers AM, Broussard BK, Taylor R, Egan MJ.   +3 more
europepmc   +1 more source