Results 51 to 60 of about 51,957 (163)

Nucleolar origins: challenging perspectives on evolution and function

Open Biology
The nucleolus, once considered a mere ‘ribosome factory’, is now recognized as a dynamic hub influencing nearly every aspect of cellular life, from genome organization to stress response and ageing.
Israel Muñoz-Velasco, Ana Karen Herrera-Escamilla, Alberto Vázquez-Salazar   +2 more
doaj   +1 more source

Single-cell laser emitting cytometry for label-free nucleolus fingerprinting

Nature Communications
The nucleolus, a recognized biomolecular condensate, serves as the hub for ribosome biogenesis within the cell nucleus. Its quantity and morphology are discernible indicators of cellular functional states.
Guocheng Fang, Zhen Qiao, Luqi Huang, Hui Zhu, Jun Xie, Tian Zhou, Zhongshu Xiong, I-Hsin Su, Dayong Jin, Yu-Cheng Chen   +9 more
doaj   +1 more source

Rna Buffering Fluorogenic Probe for Nucleolar Morphology Stable Imaging And Nucleolar Stress‐Generating Agents Screening

Advanced Science
In the realm of cell research, membraneless organelles have become a subject of increasing interest. However, their ever‐changing and amorphous morphological characteristics have long presented a formidable challenge when it comes to studying their ...
Wenchao Jiang, Qinglong Qiao, Jie Chen, Pengjun Bao, Yi Tao, Yinchan Zhang, Zhaochao Xu   +6 more
doaj   +1 more source

REBELOTE, a regulator of floral determinacy in Arabidopsis thaliana, interacts with both nucleolar and nucleoplasmic proteins

FEBS Open Bio, 2018
The nucleoplasm and nucleolus are the two main territories of the nucleus. While specific functions are associated with each of these territories (such as mRNA synthesis in the nucleoplasm and ribosomal rRNA synthesis in the nucleolus), some proteins are
Stève de Bossoreille, Patrice Morel, Christophe Trehin, Ioan Negrutiu   +3 more
doaj   +1 more source

Long Noncoding RNAs and Stress Response in the Nucleolus

Cells, 2019
Long noncoding RNAs (lncRNAs) perform diverse functions in the regulation of cellular processes. Here we consider a variety of lncRNAs found in the ribosome production center, the nucleolus, and focus on their role in the response to environmental ...
Sergei A. Pirogov, Vladimir A. Gvozdev, Mikhail S. Klenov   +2 more
doaj   +1 more source

The nucleolus [PDF]

Current Biology, 2000
Lyon, C. E., Lamond, A. I.
openaire   +3 more sources

Nucleolus: the ribosome factory.

Histology and histopathology, 2008
The nucleolus is a nuclear compartment and represents the most obvious and clearly differentiated nuclear structure seen in the microscope. Within nucleoli most events of ribosome biogenesis, such as ribosomal RNA synthesis, processing, and ribosome subunit assembly, take place.
Cmarko, Dusan, Smigova, Jana, Minichova, Lucía, Popov, Alexey   +3 more
openaire   +3 more sources

The nucleolus [PDF]

Journal of Cell Science, 2005
Lam, Yun Wah, Trinkle-Mulcahy, Laura, Lamond, Angus I.   +2 more
openaire   +3 more sources

PNAC: a protein nucleolar association classifier

BMC Genomics, 2011
Background Although primarily known as the site of ribosome subunit production, the nucleolus is involved in numerous and diverse cellular processes. Recent large-scale proteomics projects have identified thousands of human proteins that associate with ...
Lamond Angus I, Boisvert François-Michel, Scott Michelle S, Barton Geoffrey J   +3 more
doaj   +1 more source

The nucleolar phase of signal recognition particle assembly

Life Science Alliance
Signal recognition particle (SRP) involved in tethering the ribosome to the endoplasmic reticulum for protein secretion is assembled in part in the nucleolus where it interacts with numerous ribosome assembly factors.
Amani Issa, Florence Schlotter, Justine Flayac, Jing Chen, Ludivine Wacheul, Manon Philippe, Lucas Sardini, Lalia Mostefa, Franck Vandermoere, Edouard Bertrand, Céline Verheggen, Denis LJ Lafontaine, Séverine Massenet   +12 more
doaj   +1 more source