Results 111 to 120 of about 72,696 (188)

Effect of NPM1 Mutation Subtype and Co‐Mutation Patterns on the Outcomes of Acute Myeloid Leukemia

European Journal of Haematology, Volume 115, Issue 1, Page 29-35, July 2025.
ABSTRACT Introduction NPM1 mutated AML without FLT3‐ITD is considered “favorable” per the recent ELN 2022 criteria. However, our center has been challenged with treatment‐refractory patients, prompting a search for additional prognostic factors. Methods We reviewed records of NPM1 AML patients from 2015 to 2024.
Kittika Poonsombudlert, Ratdanai Yodsuwan, Sarah Mott, Kathryn Crawford, Sarah Hornberg, Anthony N. Snow, Grerk Sutamtewagul, Margarida Magalhaes‐Silverman, Prajwal Dhakal   +8 more
wiley   +1 more source

GPATCH4 functions as a regulator of nucleolar R-loops in hepatocellular carcinoma cells. [PDF]

Nucleic Acids Res
Zhao YM, Jiang Y, Wang JZ, Cao S, Zhu H, Wang WK, Yu J, Liu J, Hui J.   +8 more
europepmc   +1 more source

A reply to mueller (2018) supply chain collaboration: Further insights into incentive alignment in the beer game scenario [PDF]

, 2018
Fernández Quesada, María Isabel, García Fernández, Nazario, Parreño Fernández, José, Ponte Blanco, Borja, Rosillo Camblor, Rafael   +4 more
core   +2 more sources

Bioinformatic Analysis of Actin-Binding Proteins in the Nucleolus During Heat Shock. [PDF]

Genes (Basel)
Taniguchi S, Torii T, Goto T, Takeuchi K, Katsumi R, Sumida M, Lee S, Sugimoto W, Gessho M, Itoh K, Hirata H, Kawakami J, Miyoshi D, Kawauchi K.   +13 more
europepmc   +1 more source

Regulation of physiological and pathological condensates by molecular chaperones

The FEBS Journal, EarlyView.
Mounting evidence suggests that stress granules (SGs), dynamic membraneless compartments involved in cellular stress responses, can transition into pathological condensates upon improper disassembly. This review discusses the evidence supporting this notion.
Nadeen Akaree, Valentina Secco, Flonia Levy‐Adam, Amal Younis, Serena Carra, Reut Shalgi   +5 more
wiley   +1 more source

SNORA47 affects stemness and chemotherapy sensitivity via EBF3/RPL11/c-Myc axis in luminal A breast cancer. [PDF]

Mol Med
Han Q, Zhou Y, Dong Z, Wang W, Wang M, Pang M, Song X, Chen B, Zheng A.   +8 more
europepmc   +1 more source

Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins [PDF]

, 2007
Abovich, Andersen, Andersen, Angus I. Lamond, Doherty, Gallagher, Granneman, Gritz, Jakel, Jens S. Andersen, Lam, Lebreton, Leung, Leung, Lewis, Lippincott-Schwartz, Mann, Matsumoto, Matthias Mann, Mayer, Misteli, Nissan, Ong, Plafker, Rockel, Ross, Schafer, Scherl, Shav-Tal, Stavreva, Steitz, Tate, Trinkle-Mulcahy, Warner, Warner, Warner, Wu, Wu, Yun Wah Lam   +38 more
core   +3 more sources

A cellular model of TDP‐43 induces phosphorylated TDP‐43 aggregation with distinct changes in solubility and autophagy dysregulation

The FEBS Journal, EarlyView.
TDP‐43 protein plays a pathological role in sporadic and familial amyotrophic lateral sclerosis (ALS). Here, we developed a cellular model overexpressing TDP‐43 with three mutations linked to familial ALS, termed ‘3X‐TDP‐43’. Mutant 3X‐TDP‐43 expression showed deficits in autophagy flux and colocalization with stress granules.
Matthew B. Dopler, Muhammad I. Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L. Petersen, Esther H. Daniel, Carlton L. Cannon III, Angelica Bautista, Kennedy D. Blancher, Alysia M. Bland, Kylie J. Bond, Dominque A. Davis, Jessica M. Francois, Eliana J. McCray, Justin M. Morgan, Jessica L. Pulliam, Zymir A. Robinson, Mykia J. Taylor, James A. Dowell, Nigel J. Cairns, Michael A. Gitcho   +20 more
wiley   +1 more source

Emerging roles for the nucleolus in development and stem cells.

Development
Leeke BJ, Staffhorst I, Percharde M.
europepmc   +1 more source

LINE-1, the NORth star of nucleolar organization. [PDF]

Genes Dev
Matsuo M, Cristofari G.
europepmc   +1 more source