Results 121 to 130 of about 51,957 (163)
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To be or not to be in the nucleolus

Nature Cell Biology, 2000
Compartmentalization has long been known to have a key role in regulation of cellular processes. By keeping enzymes and regulatory complexes in compartments where the delivery of substrate or exit of product is controlled, competing reactions can occur simultaneously in different parts of the cell.
M, Carmo-Fonseca   +2 more
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The least square nucleolus is a general nucleolus

International Journal of Game Theory, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Elisenda Molina, Juan Tejada
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The multifunctional nucleolus

Nature Reviews Molecular Cell Biology, 2007
The nucleolus is a distinct subnuclear compartment that was first observed more than 200 years ago. Nucleoli assemble around the tandemly repeated ribosomal DNA gene clusters and 28S, 18S and 5.8S ribosomal RNAs (rRNAs) are transcribed as a single precursor, which is processed and assembled with the 5S rRNA into ribosome subunits.
Boisvert, François-Michel   +3 more
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Nucleolus and Apoptosis

Annals of the New York Academy of Sciences, 2002
Abstract: The nucleolus represents a highly dynamic nuclear compartment of the interphase nucleus. It plays a key role in ribosome biogenesis. The number of nucleoli, their size, and their activity increase in exponentially growing cells; therefore these parameters reflect the proliferating activity of the cells.
M, Horký   +3 more
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Axiomatization of the Nucleolus

Mathematics of Operations Research, 1995
An axiomatization of the nucleolus on the set of all cooperative games with finite player set is provided. The nucleolus is shown to be completely characterized by singlevaluedness, anonymity, covariance and a new reduced game property.
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The Dynamics of the Nucleolus

Critical Reviews in Eukaryotic Gene Expression, 2003
The nucleolus is the most prominent structure within the eukaryotic cell nucleus and is the site where ribosomal RNAs (5.8S, 18S, and 28S) are transcribed, processed, and assembled with ribosomal proteins to form ribosomal subunits. A role in ribosome biogenesis alone, however, does not account for the specific nucleolar localizations of tumor ...
Leung, Anthony K.L., Lamond, Angus I.
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Ribozymes in the Nucleolus

Science, 1999
Ribozymes are RNA molecules that behave like enzymes, cleaving other RNA transcripts into pieces. They have potential therapeutic value because they can be designed to chew up viral RNAs or to repair damaged mRNA transcripts. However, getting the ribozyme to the correct part of the cell where the target RNA resides is a challenge.
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The nucleolus today

Journal of Cell Science, 1991
ABSTRACT The nucleolus, the most prominent feature of the inter-phase nucleus, is involved in ribosome biogenesis (Warner, 1990). During evolution, the nucleolus first appeared at the time when nuclear envelope compartmentation of the cells was taking place. I would like in this review to provide information showing that the nucleolus is
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The nucleolus

2019
The nucleolus forms at nucleolus organizer regions (NORs) that consist of clusters of repeated rRNA genes. Transcription of the rRNA genes and processing of the transcripts yields the three types of RNAs necessary for the biogenesis of ribosomes. Only subsets of the rRNA genes present in cells are transcribed.
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The nucleolus

2009
The nucleolus is the most prominent subnuclear compartment in eukaryotic cells. It has a central function in the biogenesis of ribosomal subunits, but the past decade has revealed that a variety of additional non-ribosomal ribonucleoprotein (RNP) complexes require passage through the nucleolus during their maturation as well.
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